PURPOSE: To determine aggregate outcomes and prognostic covariates in patients with
recurrent glioma enrolled onto phase II chemotherapy trials. PATIENTS AND METHODS …

Low-grade gliomas typically are diagnosed in young adults and have a peak incidence in
the third and fourth decades. Even though these lesions are characterized by the absence of …

Results: Forty-eight patients received carboplatin/cysplatin as second line chemotherapy for
recurrent HGG (grade III n= 6; grade IV n= 42). The median number of cycles completed was …

Background The majority of patients with glioblastoma (GBM) experience disease
progression. At recurrence, treatment options have limited efficacy. Many studies report a …

There is considerable variability in the management of diffuse low-grade gliomas (LGGs). To
characterize treatment paradigms, a survey of Canadian neurosurgeons was performed with …

PURPOSE To review the outcomes of patients with low-grade glioma diagnosed by modern
imaging and treated at a center where postponing radiotherapy was common practice …

2025 Background: Low-grade gliomas (LGG) account for 17-22% of all primary brain tumors.
Optimal surgical management consists of optimum safe resection with the goal of complete …

Background: The EORTC Trial 22845 on the role of immediate postoperative radiotherapy in
patients with supratentorial lowgrade glioma revealed an advantage of immediate …

Object. It is standard practice for the oncological follow-up of patients with brain tumors
(especially in the setting of clinical trials) to include neurological examination and …