Regulation of energy homeostasis is tightly controlled by the central nervous system (CNS).
Several key areas such as the hypothalamus and brainstem receive and integrate signals …

Body weight is determined by a balance between food intake and energy expenditure.
Multiple neural circuits in the brain have evolved to process information about food, food …

Introduction 3. The central anatomy of energy-related neuronal network 3.1. The
hypothalamus 3.2. The Arcuate nucleus and the melanocortin pathway 3.3. Second order …

Obesity is a rapidly increasing public health concern worldwide as a major risk factor for
numerous disorders, including diabetes, hypertension and heart disease. Despite …

Adipose tissue, defined as white adipose tissue (WAT) and brown adipose tissue (BAT), is a
biological caloric reservoir; in response to over-nutrition it expands and, in response to …

The incidence of obesity and its related disorders are increasing at a rate of pandemic
proportions. Understanding the mechanisms behind the maintenance of energy balance is …

It has long been known, in large part from animal studies, that the control of brown adipose
tissue (BAT) thermogenesis is insured by the central nervous system (CNS), which …

Body weight is tightly controlled in a species-specific range from insects to vertebrates and
organisms have developed a complex regulatory network in order to avoid either excessive …

In healthy individuals, energy intake is in balance with energy expenditure, which helps to
maintain a normal body weight. The brain's inability to control energy homeostasis underlies …

The central nervous system (CNS) receives information from afferent neurons, circulating
hormones, and absorbed nutrients and integrates this information to orchestrate the actions …