Increased tolerance to central hypovolemia is generally associated with greater
sympathoexcitation, high‐frequency oscillatory patterns of mean arterial pressure (MAP) …

Abstract mdash;: The aim of the present study was to examine the role of opiate receptor
activation in modulating the hemodynamic, neuroendocrine, and tissue (lung and spleen) …

Background To study the influence of morphine on chemical control of breathing relative to
the analgesic properties of morphine, the authors quantified morphine-induced analgesia …

New Findings• What is the central question of this study? Simulated haemorrhage increases
ventilation prior to presyncope, possibly increasing venous return through the respiratory …

Lower body negative pressure (LBNP), a model of hemorrhage (Hem), shifts blood to the
legs and elicits central hypovolemia. This study compared responses to LBNP and actual …

Plasma osmolality alters control of sympathetic activity and heart rate in animal models;
however, it is unknown whether physiological increases in plasma osmolality have such …

Circulatory shock and pain were associated as frequent consequences of surgery and
trauma prior to the development of anesthetics. The recent discovery of the endogenous …

This study explored the concept that morphine has latent deleterious actions on the
ventilatory control systems that respond to a hypoxic-hypercapnic challenge. In this study …

Major bleeding is one of the most frequently occurring medical conditions that require the
attention of physicians and surgeons. The most frequent causes of major bleeding in most …

BACKGROUND: A recently published study from our laboratory demonstrated that morphine
sulfate (MS) attenuates microvascular hyperpermeability after hemorrhagic shock in rats. MS …