Aims To compare the analgesic effect of morphine combined with maropitant and/or
dexmedetomidine to morphine alone but at a higher dose, and to evaluate the …

The purpose of this study was to evaluate the pharmacokinetics of morphine in combination
with dexmedetomidine and maropitant injected intramuscularly in dogs under general …

Objective To determine if the combinations of morphine, dexmedetomidine and maropitant
enhance the analgesic effect and decrease the dose of individual drugs in rats subjected to …

This study was conducted to compare the efficacy of combinations of morphine,
dexmedetomidine and maropitant in preventing the changes in electroencephalographic …

Opioids are an important component of multi-modal analgesia techniques. Different classes
of analgesic drugs, when used concurrently, will modulate the pain pathway at different …

This article analyses the pharmacological considerations when administering opioids in
practice. Beginning with a basic review of pain pathways, followed by a more in-depth …

Background Multimodal analgesia consists of the combination of analgesic drugs at low
doses to act in different places along the path of pain. Studies with continuous infusion of …

The recent improvement in understanding pain, in terms of perception, transmission,
modulation, and the development of a wide spectrum of analgesic compounds has led …

Simple Summary Opioids such as methadone are the most potent and most used analgesic
drugs in anesthetic protocols, but they have several dose-dependent adverse effects. Some …

The aim of this study was to analyze the analgesic effect of maropitant, compared to isolated
morphine or combination of both drugs, when used as pre-anesthetic medication in elective …