Oxytocin (OT) has been implicated in the cardiovascular responses to exercise, stress, and
baroreflex adjustments. Studies were conducted to determine the effect of genetic …

Obesity is important for the development of type-2 diabetes as a result of obesity-induced
insulin resistance accompanied by impaired compensation of insulin secretion from …

Oxytocin (OT), traditionally associated with reproductive functions, was revisited recently,
which revealed several new functions of the hormone in cardiovascular regulation. To …

Background: In addition to the well-known role played in lactation and parturition, Oxytocin
(OT) and OT receptor (OTR) are involved in many other aspects such as the control of …

This work shows long-term restoration of the hypothalamic oxytocin (OXT) network
preserves OXT release, reduces mortality, cardiac inflammation, fibrosis, and improves …

Previous studies demonstrated the presence of oxytocin (OT) and oxytocin receptors (OTRs)
in the heart. The present work provides results supporting a potential role of OT in …

Background: We investigated whether postinfarct treatment with oxytocin (OT) improves left
ventricular (LV) function and remodeling via cardiac repair of myocardial ischemia …

Aim Oxytocin administration to diet-induced obese (DIO) rodents, monkeys and humans
decreases body weight and fat mass with concomitant improvements in glucose metabolism …

Oxytocin is synthesized and released in the heart and vasculature, tissues that also express
oxytocin receptors. Although it has been established this intrinsic cardiovascular oxytocin …

Cardiac oxytocin (OT) is structurally identical to that found in the hypothalamus, which
thereby indicates that cardiac OT is derived from the same gene and is an active form of OT …