Genomic and transcriptomic differences in community acquired methicillin resistant Staphylococcus aureus USA300 and USA400 strains

MB Jones, CP Montgomery, S Boyle-Vavra, K Shatzkes… - BMC genomics, 2014 - Springer
Background Staphylococcus aureus is a human pathogen responsible for substantial
morbidity and mortality through its ability to cause a number of human infections including …

Genetic structure of community acquired methicillin-resistant Staphylococcus aureus USA300

R Tewhey, CR Cannavino, JAD Leake, V Bansal… - BMC genomics, 2012 - Springer
Background Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA)
is a significant bacterial pathogen that poses considerable clinical and public health …

Pan-genomic perspective on the evolution of the Staphylococcus aureus USA300 epidemic

DM Jamrozy, SR Harris, N Mohamed… - Microbial …, 2016 - microbiologyresearch.org
Staphylococcus aureus USA300 represents the dominant community-associated methicillin-
resistant S. aureus lineage in the USA, where it is a major cause of skin and soft tissue …

Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance

MTG Holden, EJ Feil, JA Lindsay… - Proceedings of the …, 2004 - National Acad Sciences
Staphylococcus aureus is an important nosocomial and community-acquired pathogen. Its
genetic plasticity has facilitated the evolution of many virulent and drug-resistant strains …

Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant Staphylococcus aureus

R Copin, WE Sause, Y Fulmer… - Proceedings of the …, 2019 - National Acad Sciences
The past two decades have witnessed an alarming expansion of staphylococcal disease
caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) …

Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus

SK Highlander, KG Hultén, X Qin, H Jiang… - BMC microbiology, 2007 - Springer
Background Community acquired (CA) methicillin-resistant Staphylococcus aureus (MRSA)
increasingly causes disease worldwide. USA300 has emerged as the predominant clone …

Genome evolution of invasive methicillin-resistant Staphylococcus aureus in the Americas

JT Smith, EM Eckhardt, NB Hansel… - Microbiology …, 2022 - Am Soc Microbiol
Staphylococcus aureus causes a variety of debilitating and life-threatening diseases, and
thus remains a challenging global health threat. S. aureus is remarkably diverse, yet only a …

Epidemic community-associated methicillin-resistant Staphylococcus aureus: Recent clonal expansion and diversification

AD Kennedy, M Otto, KR Braughton… - Proceedings of the …, 2008 - National Acad Sciences
Emerging and re-emerging infectious diseases, especially those caused by drug-resistant
bacteria, are a major problem worldwide. Community-associated methicillin-resistant …

Reemergence of antibiotic-resistant Staphylococcus aureus in the genomics era

FR DeLeo, HF Chambers - The Journal of clinical …, 2009 - Am Soc Clin Investig
Staphylococcus aureus is the leading cause of bacterial infections in developed countries
and produces a wide spectrum of diseases, ranging from minor skin infections to fatal …

A prospective cohort multicenter study of molecular epidemiology and phylogenomics of Staphylococcus aureus bacteremia in nine Latin American countries

CA Arias, J Reyes, LP Carvajal, S Rincon… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Staphylococcus aureus is an important pathogen causing a spectrum of diseases ranging
from mild skin and soft tissue infections to life-threatening conditions. Bloodstream infections …