Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disease that recapitulates
many symptoms of physiological aging and precipitates death. Patients develop severe …

Hutchinson–Gilford Progeria Syndrome (HGPS) is a segmental premature aging disease
causing patient death by early teenage years from cardiovascular dysfunction. Although …

Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare genetic disorder for
which no cure exists. The disease is characterized by premature aging and inevitable death …

Background: Progerin, an aberrant protein that accumulates with age, causes the rare
genetic disease Hutchinson-Gilford progeria syndrome (HGPS). Patients who have HGPS …

Cardiovascular disease (CVD) is the main cause of death worldwide, and aging is its
leading risk factor. Aging is much accelerated in Hutchinson–Gilford progeria syndrome …

Background: Hutchinson-Gilford progeria syndrome (HGPS) is a rare disorder characterized
by premature aging and death mainly because of myocardial infarction, stroke, or heart …

Introduction 3. Hutchinson-Gilford progeria syndrome and cardiovascular dysfunction 4.
Progerin and pre-lamin A as potential new elements contributing to vascular dysfunction …

Aging, the main risk factor for cardiovascular disease (CVD), is becoming progressively
more prevalent in our societies. A better understanding of how aging promotes CVD is …

Objective—Children with Hutchinson-Gilford progeria syndrome (HGPS) exhibit dramatically
accelerated cardiovascular disease (CVD), causing death from myocardial infarction or …

Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder with features of
accelerated aging. The majority of HGPS cases are caused by a de novo point mutation in …