Background Oxidative stress is known to be involved in the development of hypertension,
but accurate redox biomarkers predicting the risk of developing hypertension are scarce …

Background Serum sulfhydryl groups (R-SH, free thiols) reliably reflect the systemic redox
status in health and disease. As oxidation of R-SH occurs rapidly by reactive oxygen species …

Background Serum free thiols (R-SH, sulfhydryl groups) reliably reflect systemic oxidative
stress. Since serum free thiols are rapidly oxidized by reactive species, systemic oxidative …

Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative
stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free …

Aims Oxidative stress is a driver in the development of type 2 diabetes (T2DM)
complications. As thiols (R-SH) are oxidized by reactive oxygen and sulfur species …

Oxidative stress plays a pivotal role in the pathogenesis of cardiovascular diseases (CVD).
Postmenopausal women have an increased risk of developing CVD due to decreased …

Hypertension is frequently associated with oxidative stress caused by high production of
reactive oxygen species and compromised antioxidant defenses. Humans with essential …

Oxidative stress plays a pivotal role in cardiovascular (CV) disease, but current biomarkers
used to predict CV events are still insufficient. In this study, we comparatively assessed the …

Background Serum thiols have shown associations with surrogate markers of cardiovascular
disease. However, little information is available on their combined association with validated …

Endothelial dysfunction is known to precede the development of atherosclerosis and results
primarily from increased oxidative degradation of NO. We hypothesized that assessment of …