Evidence for oxidative stress in essential hypertension: perspective for antioxidant therapy

T Parik, K Allikmets, R Teesalu… - … of Cardiovascular Risk, 1996 - journals.sagepub.com
Background Despite therapy, arterial hypertension continues to be a risk factor of coronary
artery disease (GAD). The role of oxidative stress, an important source of vascular injury, in …

Oxidative stress and hyperinsulinaemia in essential hypertension: different facets of increased risk

R Teesalu, K Allikmets, M Zimer - Journal of hypertension, 1996 - journals.lww.com
Objective: To evaluate oxidative stress markers in normo and hyperinsulinaemic essential
hypertension patients, and to relate these parameters to plasma glucose and insulin levels …

Serum free sulfhydryl status is associated with patient and graft survival in renal transplant recipients

ARS Frenay, MH de Borst, M Bachtler… - Free Radical Biology …, 2016 - Elsevier
Oxidative stress contributes significantly to graft failure, morbidity and mortality in renal
transplant recipients (RTR). In cells, free sulfhydryl groups (reduced thiols, R-SH) are the …

[HTML][HTML] The systemic redox status is maintained in non-smoking type 2 diabetic subjects without cardiovascular disease: association with elevated triglycerides and …

PR van Dijk, AE Abdulle, MLC Bulthuis… - Journal of Clinical …, 2019 - mdpi.com
Decreased circulating levels of free thiols (R-SH, sulfhydryl groups) reflect enhanced
oxidative stress, which plays an important role in the pathogenesis of cardiometabolic …

Plasma total cysteine and cardiovascular risk burden: action and interaction

B De Chiara, V Sedda, M Parolini… - The Scientific World …, 2012 - Wiley Online Library
We hypothesized that redox analysis could provide sensitive markers of the oxidative
pathway associated to the presence of an increasing number of cardiovascular risk factors …

The association between pre-hypertension status and oxidative stress markers related to atherosclerotic disease: the ATTICA study

C Chrysohoou, DB Panagiotakos, C Pitsavos… - Atherosclerosis, 2007 - Elsevier
BACKGROUND: We sought to evaluate the association between pre-hypertension status
and oxidative stress markers (total antioxidant capacity (TAC) and oxidized low density …

Systemic transsulfuration pathway thiol concentrations in chronic obstructive pulmonary disease patients

A Zinellu, E Zinellu, E Sotgiu, AG Fois… - European Journal of …, 2020 - Wiley Online Library
Background It is amply reported that patients with chronic obstructive pulmonary disease
(COPD) have increased risk of cardiovascular disease (CVD). Recent evidence suggests …

Serum thioredoxin and α-tocopherol concentrations in patients with major risk factors

K Miwa, C Kishimoto, H Nakamura, T Makita… - Circulation …, 2005 - jstage.jst.go.jp
Background Oxidative stress, which is thought to be increased in subjects with various
coronary risk factors, induces thioredoxin (TRX), a redox-active protein. Methods and …

Homocysteine and red blood cell glutathione as indices for middle-aged untreated essential hypertension patients

P Muda, P Kampus, M Zilmer, K Zilmer… - Journal of …, 2003 - journals.lww.com
Objective Intracellular glutathione in its reduced state is a principal cellular biomolecule with
antioxidant activity. Glutathione and homocysteine metabolism are closely associated. As …

[PDF][PDF] Role of glutathione metabolism and glutathione-related antioxidant defense systems in hypertension

J Robaczewska, K Kedziora-Kornatowska… - J Physiol …, 2016 - jpp.krakow.pl
The risk of developing chronic hypertension increases with age. Among others factors,
increased oxidative stress is a well-recognized etiological factor for the development of …