Objectives Our aim was to assess the reliability of nailfold capillary assessment in terms of
image evaluability, image severity grade ('normal','early','active','late'), capillary density …

Background Nailfold capillaroscopic parameters hold increasing promise as outcome
measures for clinical trials in systemic sclerosis (SSc). Their inclusion as outcomes would …

Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by
early impairment of the microvascular system. Nailfold microangiopathy and decreased …

Microvascular damage and a decrease in peripheral blood perfusion are typical features of
systemic sclerosis (SSc) with serious clinical implications, not only for a very early diagnosis …

Nailfold microvascular impairment represents an early feature of systemic sclerosis (SSc)
and its progression through different patterns of capillary damage and their validated …

Introduction: Nailfolds of patients with systemic sclerosis (SSc) provide an opportunity to
directly visualize microvascular remodeling in SSc. Nailfold video capillaroscopy (NVC) …

Objectives Despite increasing interest in nailfold capillaroscopy, objective measures of
capillary structure and blood flow have been little studied. We aimed to test the hypothesis …

Background Absolute nailfold capillary number should be a putative biomarker in selected
rheumatic diseases but could be time‐consuming and not highly repeatable. Objective To …

Systemic sclerosis is an autoimmune connective tissue disease characterized by early and
persistent microvascular impairment which leads to functional and organic manifestations …

Objective The aim of this observational study was to investigate the evolution of scleroderma
microangiopathy throughout different nailfold videocapillaroscopy (NVC) patterns …