• MCR antagonists are further categorized into steroidal and nonsteroidal MCR antagonists.•
ACE inhibitors and ARBs are among the four first-line agents used in the treatment of …

The renin angiotensin aldosterone (RAA) system plays a central role in regulating
cardiovascular and renal functions and is a key component of the blood pressure …

BACKGROUND: The renin-angiotensin aldosterone system (RAAS) is a hormonal cascade
that functions in the homeostatic control of arterial pressure, tissue perfusion, and …

Since the description in 1977 of the first angiotensin-converting enzyme (ACE) inhibitor,
captopril, by the Squibb group led by Ondetti and Cushman, ACE inhibitors have become …

Agents that block the renin-angiotensin-aldosterone system (RAAS) are the cornerstones of
antihypertensive therapy in patients at high risk for cardiovascular or renal disease …

Atlas's research has focused on the renin-angiotensin system and the natriuretic peptide
hormone family. He was one of the first investigators to study the ACE inhibitors …

The renin-angiotensin-aldosterone system (RAAS) plays a pivotal role in the pathogenesis
of hypertension (HTN). Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II …

Renin–angiotensin–aldosterone system inhibitors. New and old approaches - ScienceDirect
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The renin–angiotensin–aldosterone system (RAAS) is a hormonal loop that regulates blood
pressure and fluid balance. This system plays a prominent role in the pathophysiology of …

The renin-angiotensin-aldosterone system (RAAS) plays an important role in blood pressure
control and volume homeostasis. Inappropriate activation of the RAAS has been implicated …