Actions of brain-derived neurotrophic factor and glucocorticoid stress in neurogenesis

T Numakawa, H Odaka, N Adachi - International journal of molecular …, 2017 - mdpi.com
Altered neurogenesis is suggested to be involved in the onset of brain diseases, including
mental disorders and neurodegenerative diseases. Neurotrophic factors are well known for …

Impact of glucocorticoid on neurogenesis

H Odaka, N Adachi, T Numakawa - Neural regeneration research, 2017 - journals.lww.com
Neurogenesis is currently an area of great interest in neuroscience. It is closely linked to
brain diseases, including mental disorders and neurodevelopmental disease. Both …

Brain-derived neurotrophic factor and glucocorticoids: reciprocal influence on the central nervous system

T Numakawa, N Adachi, M Richards, S Chiba… - Neuroscience, 2013 - Elsevier
Brain-derived neurotrophic factor (BDNF) has multiple roles in the central nervous system
(CNS), including maintaining cell survival and regulation of synaptic function. In CNS …

Corticotropin-releasing hormone exerts direct effects on neuronal progenitor cells: implications for neuroprotection

Y Koutmani, PK Politis, M Elkouris, G Agrogiannis… - Molecular …, 2013 - nature.com
Neurogenesis during embryonic and adult life is tightly regulated by a network of
transcriptional, growth and hormonal factors. Emerging evidence indicates that activation of …

Glucocorticoid receptor represses brain-derived neurotrophic factor expression in neuron-like cells

H Chen, M Lombès, D Le Menuet - Molecular brain, 2017 - Springer
Brain-derived neurotrophic factor (BDNF) is involved in many functions such as neuronal
growth, survival, synaptic plasticity and memorization. Altered expression levels are …

Actions of brain-derived neurotrophin factor in the neurogenesis and neuronal function, and its involvement in the pathophysiology of brain diseases

T Numakawa, H Odaka, N Adachi - International journal of molecular …, 2018 - mdpi.com
It is well known that brain-derived neurotrophic factor, BDNF, has an important role in a
variety of neuronal aspects, such as differentiation, maturation, and synaptic function in the …

Brain‐derived neurotrophic factor stimulates proliferation and differentiation of neural stem cells, possibly by triggering the Wnt/β‐catenin signaling pathway

BY Chen, X Wang, ZY Wang, YZ Wang… - Journal of …, 2013 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) has critical functions in promoting survival,
expansion, and differentiation of neural stem cells (NSCs), but its downstream regulation …

[HTML][HTML] Functional interactions between steroid hormones and neurotrophin BDNF

T Numakawa, D Yokomaku, M Richards… - World Journal of …, 2010 - ncbi.nlm.nih.gov
Brain-derived neurotrophic factor (BDNF), a critical neurotrophin, regulates many neuronal
aspects including cell differentiation, cell survival, neurotransmission, and synaptic plasticity …

Sex and stress hormone influences on the expression and activity of brain-derived neurotrophic factor

DL Carbone, RJ Handa - Neuroscience, 2013 - Elsevier
The neurotrophin, brain-derived neurotrophic factor (BDNF), is recognized as a key
component in the regulation of CNS ontogeny, homeostasis and adult neuroplasticity. The …

[HTML][HTML] The role of BDNF on neural plasticity in depression

T Yang, Z Nie, H Shu, Y Kuang, X Chen… - Frontiers in cellular …, 2020 - frontiersin.org
Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …