Are monotherapies still valuable to the treatment of hypertension?

AFG Cicero, M Landolfo, C Borghi - Expert Opinion on …, 2020 - Taylor & Francis
Arterial Hypertension (AH) has a high prevalence in the population worldwide and
represents the most important risk factor for cardiovascular (CV) mortality and morbidity. The …

Hypertension 2010: what was new for the cardiologist?

Z Gaciong, B Symonides - Expert Opinion on Pharmacotherapy, 2010 - Taylor & Francis
Importance of the field: Despite extensive clinical research, still there is some uncertainty
regarding management of hypertension, in particular initial and goal blood pressure levels …

Ongoing clinical trials in systemic hypertension

P Oddou, J Mann - Expert Opinion on Investigational Drugs, 2001 - Taylor & Francis
Hypertension was identified as a cardiovascular risk factor in the late fifties and still remains
a public health issue. The number of patients treated reaches only half of those diagnosed …

State-of-the-art treatment of hypertension: established and new drugs

M Burnier, Y Vuignier, G Wuerzner - European heart journal, 2014 - academic.oup.com
The treatment of essential hypertension is based essentially on the prescription of four major
classes of antihypertensive drugs, ie blockers of the renin–angiotensin system, calcium …

Key articles and guidelines in the management of hypertension: 2008 update

SM Gaffney, S de Denus, KL Olson… - … : The Journal of …, 2008 - Wiley Online Library
Hypertension remains a major risk factor for cardiovascular disease. The optimal choice of
pharmacologic and nonpharmacologic treatment regimens is based on a plethora of …

Treatment of hypertension: which goal for which patient?

F Jarraya - Hypertension: from basic research to clinical practice, 2017 - Springer
Hypertension remains the most important risk factor for cardiovascular disease. If
antihypertensive drugs choice is well guided today, blood pressure (BP) target still a subject …

Arterial Hypertension-when are which combination therapies useful?

R Brenner, SF Rimoldi, E Rexhaj… - Therapeutische …, 2012 - europepmc.org
Arterial hypertension is a widely prevalent risk factor for cardiovascular diseases with well
documented harmful effects on the heart and the vascular system. Despite a broad …

HYPERTENSION: MONOTHERAPY AND COMBINATION THERAPY

M Burnier, G Wuerzner, B Waeber - Manual of Hypertension, 2014 - api.taylorfrancis.com
In the late 1960s and early 1970s, Freis et al. demonstrated convincingly that the
administration of antihypertensive drugs was associated with a marked reduction in target …

Management of hypertension: evidence from the Blood Pressure Lowering Treatment Trialists' Collaboration and from major clinical trials.

J Chalmers, H Arima - Polskie Archiwum Medycyny Wewnetrznej, 2009 - europepmc.org
Deciding who to treat should be based on estimation of the total cardiovascular risk, not just
the blood pressure (BP), so that patients with established cardiovascular disease or at high …

Managing hypertension in high-risk patients: lessons and promises from the STRATHE and ADVANCE trials

B Waeber - Journal of Hypertension, 2006 - journals.lww.com
Pharmacological treatment of hypertension represents a cost-effective way of preventing
cardiovascular and renal complications. To benefit maximally from antihypertensive …