Crocus sativus L.(saffron) has been used as a spice and as a medicine for the past four
thousand years. Recently, saffron has been well documented to possess anticancer effects …

Triple-negative breast cancer (TNBC) is the most metastatic subtype of breast cancer and
cannot be controlled with any standard-of-care therapy. However, various studies have …

Aim To determine the anti-metastatic potential of combinations of two bioactive carotenoids
of saffron, crocin and crocetin, on 4T1 breast cancer and on a mice model of TNBC, and …

Abstract Crocus sativus L.(saffron), was applied as a spice, food colorant and medicine
since four millennia ago and has been used as a remedy for various maladies. In the last …

Crocetin is a carotenoid dicarboxylic acid which, in nature, is esterified with glucose or
gentiobiose units forming the crocins, abundant components of saffron (a spice with many …

Objectives Crocin is derived from dried stigmas of Crocus sativus L.(saffron). It has long
been used to prevent and treat various diseases. Although crocin is suggested as one of the …

Gastric cancer (GC) is one of the major causes of cancer-related deaths and
chemoresistance is a key obstacle to the treatment of GC, particularly in advanced GC. As …

Breast cancer (BC) is the most commonly diagnosed cancer confronting women worldwide.
Crocin, a glycosylated carotenoid extracted from Crocus sativus L., possesses anti-cancer …

Angiogenesis and metastasis play pivotal roles in the progression of cancer. We recently
discovered that crocin, a dietary carotenoid derived from the Himalayan crocus, inhibited the …

Cancer is one of the leading causes of death in the United States and accounts for
approximately 8 million deaths per year worldwide. Although there is an increasing number …