The effect of dietary trans α-linolenic acid on plasma lipids and platelet fatty acid composition: the TransLinE study

JL Sébédio, SHF Vermunt, JM Chardigny… - European journal of …, 2000 - nature.com
Objective: To collect (i) baseline data and (ii) execute a large multicentre study examining
the effect of trans α-linolenic acid on its incorporation into plasma lipids and on risk factors …

[HTML][HTML] Dietary intake of α-linolenic acid and risk of fatal ischemic heart disease among women

FB Hu, MJ Stampfer, JAE Manson, EB Rimm… - The American journal of …, 1999 - Elsevier
Background Experimental studies in laboratory animals and humans suggest that α-linolenic
acid (18: 3n− 3) may reduce the risk of arrhythmia. Objective The objective was to examine …

[PDF][PDF] Alpha-linolenic acid and cardiovascular diseases. Omega-3 fatty acids beyond eicosapentaenoic acid and docosahexaenoic acid

F Nannicini, F Sofi, G Avanzi, R Abbate… - Minerva …, 2006 - flore.unifi.it
Over the last decades, an increasing body of evidence has been accumulated on the
beneficial effect of polyunsaturated fatty acids both in primary and secondary prevention of …

Effect of dietary alpha-linolenic acid on blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials

H Su, R Liu, M Chang, J Huang, Q Jin… - European journal of …, 2018 - Springer
Purpose The aim of the current meta-analysis was to investigate the effect of increasing
dietary ALA intake on the blood concentration of inflammatory markers including tumor …

Increased α-linolenic acid intake lowers C-reactive protein, but has no effect on markers of atherosclerosis

WJE Bemelmans, JD Lefrandt, EJM Feskens… - European Journal of …, 2004 - nature.com
Objective: To investigate the effects of increased alpha-linolenic acid (ALA)-intake on intima–
media thickness (IMT), oxidized low-density lipoprotein (LDL) antibodies, soluble …

Plant n-3 PUFA intake may lower the risk of atherosclerotic cardiovascular disease only among subjects with a low intake of marine n-3 PUFAs

CS Bork, S Lundbye-Christensen, SK Venø… - European Journal of …, 2022 - Springer
The role of the major plant-derived n-3 PUFA, alpha-linolenic acid (ALA), on the risk of
atherosclerotic cardiovascular (ASCVD) remains unclear, but most studies have reported no …

[HTML][HTML] Increased dietary α-linolenic acid has sex-specific effects upon eicosapentaenoic acid status in humans: re-examination of data from a randomised, placebo …

CE Childs, S Kew, YE Finnegan, AM Minihane… - Nutrition journal, 2014 - Springer
Background There is a metabolic pathway by which mammals can convert the omega-3 (n-
3) essential fatty acid α-linolenic acid (ALA) into longer-chain n-3 polyunsaturated fatty acids …

Dietary α-linolenic acid and health-related outcomes: a metabolic perspective

GC Burdge, PC Calder - Nutrition research reviews, 2006 - cambridge.org
α-Linolenic acid (αLNA; 18: 3n-3) is essential in the human diet, probably because it is the
substrate for the synthesis of longer-chain, more unsaturated n-3 fatty acids, principally EPA …

[HTML][HTML] Dietary intake of α-linolenic acid and risk of age-related macular degeneration

J Wu, E Cho, EL Giovannucci, BA Rosner… - The American Journal of …, 2017 - Elsevier
Background: The relation between α-linolenic acid (ALA), a plant-derived omega-3 (n–3)
fatty acid, and age-related macular degeneration (AMD) is unclear. European researchers …

[HTML][HTML] α-Linolenic acid, linoleic acid, coronary artery disease, and overall mortality

E Vos, SC Cunnane - The American journal of clinical nutrition, 2003 - ajcn.nutrition.org
The study by Djoussé et al (1) concludes that a higher intake of both α-linolenic (18: 3nJ3)
and linoleic acid (18: 2nJ6) is inversely related to the risk of coronary artery disease (CAD) …