Rapid declines in coronary heart disease mortality in Eastern Europe are associated with increased consumption of oils rich in alpha-linolenic acid

W Zatonski, H Campos, W Willett - European journal of epidemiology, 2008 - Springer
During the 1980's, opposing time trends were observed in coronary heart disease (CHD)
rates between Eastern and Western European countries. In all former socialistic economic …

[HTML][HTML] The effects of linoleic acid consumption on lipid risk markers for cardiovascular disease in healthy individuals: A review of human intervention trials

E Froyen, B Burns-Whitmore - Nutrients, 2020 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death worldwide. Risk factors for
developing this disease include high serum concentrations of total cholesterol, triglycerides …

Harmful, harmless or helpful? The n-6 fatty acid debate goes on

PC Calder, RJ Deckelbaum - … in Clinical Nutrition & Metabolic Care, 2011 - journals.lww.com
Last year in our Editorial [1] we highlighted the then recent American Heart Association
(AHA) advice to consume at least 5–10% of energy as n-6 polyunsaturated fatty acids …

Effect of altered dietary n-3 fatty acid intake upon plasma lipid fatty acid composition, conversion of [13C] α-linolenic acid to longer-chain fatty acids and partitioning …

GC Burdge, YE Finnegan, AM Minihane… - British Journal of …, 2003 - cambridge.org
The effect of increased dietary intakes of α-linolenic acid (ALNA) or eicosapentaenoic acid
(EPA) and docosahexaenoic acid (DHA) for 2 months upon plasma lipid composition and …

[HTML][HTML] Plasma α-linolenic and long-chain ω-3 fatty acids are associated with a lower risk of acute myocardial infarction in Singapore Chinese adults

Y Sun, WP Koh, JM Yuan, H Choi, J Su, CN Ong… - The Journal of …, 2016 - Elsevier
Background: Long-chain marine omega-3 polyunsaturated fatty acids (n–3 PUFAs) are
associated with a lower risk of acute myocardial infarction (AMI), but results for plant-derived …

Marine n-3 Fatty Acids and the Risk of Peripheral Arterial Disease

AN Lasota, MLM Grønholdt, CS Bork… - Journal of the American …, 2018 - jacc.org
Background: The content of marine n-3 polyunsaturated fatty acids (PUFAs) in adipose
tissue is considered a long-term biomarker for the body's endogenous exposure to seafood …

[HTML][HTML] Evaluation of Influencing Factors on Metabolism of Land-Based n-3 Poly Unsaturated Fatty Acids—The KoALA Study

T Drobner, TS Braun, M Kiehntopf, P Schlattmann… - Nutrients, 2023 - mdpi.com
This study aimed to investigate the impact of influencing factors (sex, eicosapentaenoic acid
(EPA) status at baseline, linoleic acid (LA) intake, milk fat intake) on the conversion of α …

[HTML][HTML] Increased α-linolenic acid intake during pregnancy is associated with higher offspring birth weight

M Phang, HU Dissanayake, RL McMullan… - Current developments in …, 2019 - Elsevier
Background The amount and type of fat in the maternal diet during pregnancy are important
contributors to fetal growth. The importance of plant-based omega-3 fatty acid (α-linolenic …

Goldilocks and the three bonds: new evidence for the conditional benefits of dietary α-linolenic acid in treating cardiovascular risk in the metabolic syndrome

BA Griffin - British Journal of Nutrition, 2012 - cambridge.org
The metabolic syndrome is probably the most common purveyor of increased CVD risk in
otherwise healthy, free-living populations. It consists of a constellation of CVD risk factors …

[HTML][HTML] Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study

Y Kawakami, H Yamanaka-Okumura, Y Naniwa-Kuroki… - Nutrition journal, 2015 - Springer
Background The effects of alpha-linolenic acid (ALA) on cardiovascular risk factors
considerably vary between published reports. Therefore, we investigated the effects of 12 …