[HTML][HTML] Clinicopathological correlation of insulin-like growth factor binding protein 3 and their death receptor in patients with gastric cancer

A Ansari, A Gheysarzadeh, A Sharifi… - Research in …, 2024 - journals.lww.com
Background and purpose: The insulin-like growth factor binding protein 3 (IGFBP-3) and its
novel death receptor (IGFBP-3R) have been exhibited to have tumor suppressor effects …

Decreased expression of Insulin-like growth factor binding protein 3 and its death receptor in association with poor prognosis of the patients with gastric cancer

A Ansari, A Gheysarzadeh, H Bakhtiari, AE Razavi… - 2020 - researchsquare.com
Background: Gastric cancer (GC) as one of the most common cancers, serves as the third
cause of cancer-related death. Insulin-like growth factor binding protein 3 (IGFBP-3) and its …

The insulin‐like growth factor binding protein‐3 and its death receptor in pancreatic ductal adenocarcinoma poor prognosis

A Gheysarzadeh, H Bakhtiari, A Ansari… - Journal of cellular …, 2019 - Wiley Online Library
Insulin‐like growth factor binding protein‐3 (IGFBP‐3) and its newly discovered death
receptor (IGFBP‐3R) have been reported to involve in a wide variety of cancers. However …

Decreased expression of insulin-like growth factor binding protein 6 is associated with gastric adenocarcinoma prognosis

C Zeng, X Feng, W Wang, L Lv, C Fang… - Oncology …, 2017 - spandidos-publications.com
The present study aimed to investigate the expression and prognostic significance of insulin‑
like growth factor binding protein 6 (IGFBP-6) in gastric adenocarcinoma. The expression of …

Decreased expression of IGFBP7 was a poor prognosis predictor for gastric cancer patients

L Liu, Z Yang, W Zhang, B Yan, Q Gu, J Jiao, X Yue - Tumor Biology, 2014 - Springer
Increasing evidence indicated that insulin-like growth factor binding protein 7 (IGFBP7) was
regarded as a potential tumor suppressor in various human cancers, but its role in gastric …

IGFBP1 is a predictive factor for haematogenous metastasis in patients with gastric cancer

Y Sato, M Inokuchi, Y Takagi, K Kojima - Anticancer Research, 2019 - ar.iiarjournals.org
Background/Aim: The clinicopathological significance and prognostic value of insulin-like
growth factor binding protein 1 (IGFBP1) in gastric cancer have not been investigated to …

Insulin-like factor binding protein-3 promotes the G1 cell cycle arrest in several cancer cell lines

C Wu, X Liu, Y Wang, H Tian, Y Xie, Q Li, X Zhang… - Gene, 2013 - Elsevier
Insulin-like growth factor binding protein-3 (IGFBP-3) is a multi-functional protein known to
induce apoptosis of various cancer cells in an insulin-like growth factor (IGF)-dependent and …

Host genetic variants in the IGF binding protein-3 impact on survival of patients with advanced gastric cancer treated with palliative chemotherapy

F Graziano, A Ruzzo, E Canestrari, V Catalano… - …, 2010 - Taylor & Francis
Aim: IGF binding protein-3 (IGFBP-3) displays growth inhibitory/proapoptotic action and
counteracts the IGF-1 tumor-promoting effects by downregulating its bioavailability. We …

Relationship between expression of IGFBP7 and clinicopathological variables in gastric cancer

Y Sato, M Inokuchi, Y Takagi, S Otsuki… - Journal of clinical …, 2015 - jcp.bmj.com
Aims Insulin-like growth factor binding protein 7 (IGFBP7) is reported to have tumour
suppressor function through an IGF-dependent pathway in various malignant tumours …

Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer

AR Ingermann, YF Yang, J Han, A Mikami… - Journal of biological …, 2010 - ASBMB
Insulin-like growth factor-binding protein-3 (IGFBP-3), a major regulator of endocrine actions
of IGFs, is a p53-regulated potent apoptotic factor and is significantly suppressed in a variety …