Calcium (Ca2+) signals initiate egg activation across the animal kingdom and in at least
some plants. These signals are crucial for the success of development and, in the case of …

Changes in the intracellular concentration of calcium ([Ca2+] i) represent a vital signaling
mechanism enabling communication among cells and between cells and the environment …

Abstract Calcium (Ca2+) signals drive the fundamental events surrounding fertilization and
the activation of development in all species examined to date. Initial studies of Ca2+ …

Interaction of sperm and egg at fertilization induces well‐coordinated molecular events
including specific recognition between species, adhesion and fusion, that lead to the …

The transition from oocyte to embryo in mammals is triggered by a series of calcium
transients. There are two distinguishing features of this signal transduction pathway. First, it …

During animal fertilizations, each oocyte or egg must produce a proper intracellular calcium
signal for development to proceed normally. As a supplement to recent synopses of …

Mammalian fertilization is accompanied by oscillations in egg cytoplasmic calcium (Ca2+)
concentrations that are critical for completion of egg activation. These oscillations are …

Abstract in mammals, the sperm activates the development of the egg by triggering a series
of oscillations in the cytosolic-free Ca2+ concentration (Ca2+ i). The sperm triggers these …

Life begins with calcium. It is the language that a sperm cell uses to respond to instructions
from the female reproductive tract to alter its swimming pattern and gain the force required to …

Fertilization causes mature oocytes or eggs to increase their concentrations of intracellular
calcium ions (Ca2+) in all animals that have been examined, and such Ca2+ elevations, in …