Gene amplification and sequencing have led to the discovery of new pathogens as agents of
disease and have enabled us to better classify microorganisms from culture. Sequence …

Features of a number of important but poorly explained human clinical syndromes strongly
indicate a microbial etiology. In these syndromes, the failure of cultivation-dependent …

Outbreaks of infectious disease often result from exposure to a common source of the
etiologic agent. Generally, the etiologic agent causing an outbreak of infection is derived …

Clinical microbiology laboratories worldwide have historically relied on phenotypic methods
(ie, culture and biochemical tests) for detection, identification and characterization of …

The recent advances in sequencing technologies have given all microbiology laboratories
access to whole genome sequencing. Providing that tools for the automated analysis of …

As in other medical fields, the availability of next generation sequencing (NGS) techniques is
about to revolutionize diagnostics of infectious diseases. The demonstration of the microbial …

Rapid molecular methods have enhanced the capabilities of laboratories to identify and
characterize microbial pathogens in greater detail. Nucleic acid amplification strategies and …

The availability of genome sequences obtained using next-generation sequencing (NGS)
has revolutionized the field of infectious diseases. Indeed, more than 38,000 bacterial and …

The diagnosis of bacterial infections can be difficult and time consuming. Rapid and reliable
molecular triage of potentially infected patients, particularly the young and the elderly, would …

Taxonomic classification is an important field of microbiology, as it enables scientists to
identify prokaryotes worldwide. Although the current classification system is still based on …