Establishment and Validation of a Transdermal Drug Delivery System for the Anti-Depressant Drug Citalopram Hydrobromide

Y Sun, Y Ni, R Wang, Z Qin, Z Liu, L Xiao, Y Liu - Molecules, 2024 - mdpi.com
To enhance the bioavailability and antihypertensive effect of the anti-depressant drug
citalopram hydrobromide (CTH) we developed a sustained-release transdermal delivery …

Preparation and evaluation of diltiazem hydrochloride diffusion-controlled transdermal delivery system

E Limpongsa, K Umprayn - AAPS PharmSciTech, 2008 - Springer
The objective was to investigate the suitable polymeric films for the development of diltiazem
hydrochloride (diltiazem HCl) transdermal drug delivery systems. Hydroxypropyl …

Transdermal route: A viable option for systemic delivery of antidepressants

AO Tijani, E Nunez, K Singh, G Khanna… - Journal of Pharmaceutical …, 2021 - Elsevier
The high rise in the population suffering from depression depicts the need for improved and
highly effective treatment options for this condition. Efforts to develop existing drugs into user …

Losartan potassium and verapamil hydrochloride compound transdermal drug delivery system: Formulation and characterization

Y Chen, Y Sun, Z Qin, S Zhang, W Chen… - International Journal of …, 2022 - mdpi.com
In this study, we developed a sustained-release transdermal delivery system containing
losartan potassium (LP) and verapamil hydrochloride (VPH). LP and VPH have low …

[PDF][PDF] Controlled drug delivery of diltiazem hydrochloride as transdermal patches: a novel approach on formulation evaluation in vitro and in vivo parameters

SS Pillai, TK Muneer, T Panneerselvam… - Research in …, 2015 - researchgate.net
A significant effort was done to formulate transdermal patches (Paranjothi 1998) of Diltiazem
Hydrochloride (DH), a benzothiazepine calcium channel blocker, mainly meant for the …

[PDF][PDF] Formulation and Characterization of diltiazem transdermal system for the treatment of hypertension

R Shukla, LK Omray - Int J Curr Pharm Res, 2016 - academia.edu
The present study deals with the formulation and characterization of matrix-type transdermal
drug delivery system (TDS) of diltiazem hydrochloride for the treatment of hypertension. The …

The feasibility study of transdermal drug delivery systems for antidepressants possessing hydrophilicity or hydrophobicity

JS Baek, JH Lim, JW So, JI Kim, TW Lee… - Journal of …, 2012 - Springer
The feasibility studies on the transdermal drug delivery systems have been performed to
avoid the systemic side-effects and gastric disorders that could be occurred due to the …

Transdermal drug delivery systems of a beta blocker: design, in vitro, and in vivo characterization

M Aqil, Y Sultana, A Ali, K Dubey, AK Najmi… - Drug Delivery, 2004 - Taylor & Francis
The matrix type transdermal drug delivery systems (TDDS) of metoprolol were prepared by
film casting technique using a fabricated stainless steel film casting apparatus and …

Development and evaluation of transdermal patches of an antihypertensive drug

R Tiwari - 2011 - search.proquest.com
Abstract Diltiazem Hydrochloride is an Antihypertensive drug belongs to the category of
calcium channel blockers. The half life is 3.7 hr, metabolized mainly in the liver and …

Preclinical Investigation of Transdermal Route for Enhanced Bio-performance of Duloxetine HCl

R Kumar, VR Sinha, L Dahiya, A Sarwal - AAPS PharmSciTech, 2023 - Springer
The aim of the study was to develop and optimise drug-in-adhesive (DIA) transdermal patch
of duloxetine HCl for enhanced drug delivery. DIA patch so developed reduced the dose …