Alzheimer's disease (AD) is behaviorally identified by progressive memory impairment and
pathologically characterized by the triad of β-amyloid plaques, neurofibrillary tangles, and …

Women carry a higher burden of Alzheimer's disease (AD) compared to men, which is not
accounted entirely by differences in lifespan. To identify the mechanisms underlying this …

Neuropsychiatric signs are critical in primary caregiving of Alzheimer patients and yet have
been relatively ignored in murine models. In the present study, APPswe/PS1 bigenic mice …

Abstract Alzheimer's disease (AD), the most common form of dementia, is an age‐
dependent progressive neurodegenerative disorder. β‐amyloid, a metabolic product of the …

The knockout mouse model, B6. 129P2-Apoetm1Unc is homozygotic for the Apolipoprotein
E (ApoE) deletion; thus, it is capable of developing hyperlipidemia and atherosclerosis but …

In addition to cognitive decline, patients with Alzheimer's disease (AD) exhibit sensory,
motor, and neuropsychiatric deficits. Many AD patients also show weight loss, suggesting …

While olfactory delayed matching-to-sample tasks have been used to assess working
memory in rats, no such tasks have been tested in mice. Olfactory delayed matching-to …

Chronic stress may be a risk factor for developing Alzheimer's disease (AD), but most
studies of the effects of stress in models of AD utilize acute adverse stressors of …

The 3xTg-AD mouse model of Alzheimer's disease (AD) has both amyloid beta plaque and
tau tangle pathology. However, the results of behavioural testing with these mice have been …

Late onset, sporadic Alzheimer's disease (AD) accounts for the vast majority of cases. Unlike
familial AD, the factors that drive the onset of sporadic AD are poorly understood, although …