Alzheimer's disease often results in impaired olfactory perceptual acuity—a potential
biomarker of the disorder. However, the usefulness of olfactory screens to serve as …

Rats and mice are the most widely used species for modelling psychiatric disease.
Assessment of these rodent models typically involves the analysis of aberrant behaviour …

Olfaction is often impaired in Alzheimer's disease (AD) and is also dysfunctional in mouse
models of the disease. We recently demonstrated that short-term passive anti-murine-Aβ …

Background Several transgenic animal models genetically predisposed to develop
Alzheimer's disease (AD)-like pathology have been engineered to facilitate the study of …

The 5XFAD mice are an early‐onset transgenic model of Alzheimer's disease (AD) in which
amyloid plaques are first observed between two and four months of age in the cortical layer …

Mouse models of Alzheimer's disease (AD) are often tested for learning and memory deficits
using visuo-spatial tasks such as the Morris water maze. Performance on these tasks is …

The triple-transgenic mouse line (3× Tg-AD) harboring PS1 M146V, APP Swe, and tau
p301L transgenes represents the only transgenic model for Alzheimer's disease (AD) to date …

Objective With recent advances in molecular genetics, mouse models have been generated
for a number of disease states. Recently, the authors and others have begun to examine …

Animal models of Alzheimer's disease (AD) can be used to determine the progressive
neurodegeneration characteristics of AD in vivo using magnetic resonance imaging (MRI) …

The function of the CA 2 region of the hippocampus is poorly understood. Although the CA 1
and CA 3 regions have been extensively studied, for years the CA 2 region has primarily …