Epidemiological and experimental data have indicated the beneficial and adverse effects of
estrogenic replacement therapy. In the present study, we explored the effect of …

Oral contraceptives containing estrogens increases the incidence of thromboembolic events.
In contrast, administration of 17β-aminoestrogens prolonged blood clotting time (BCT) in …

Objectives: This work evaluated chronic treatment with 17β-oestradiol (E 2) and 17β-
aminoestrogen pentolame (AEP) on prothrombin time (PT), activated partial thromboplastin …

Oral contraceptives containing estrogens increases the incidence of thromboembolic events.
In contrast, administration of 17beta-aminoestrogens prolonged blood clotting time (BCT) in …

Administration of exogenous estrogens has been associated with an increase of
thromboembolic events. The 17β-aminoestrogens produce anticoagulant effects contrasting …

Ethinyl estradiol (EE) is still used to some extent as hormonal replacement therapy (HRT) in
the climacteric period. As regards oral contraception, it is well known that the induced …

INTRODUCTION: Rats and mice have been used to evaluate effects of natural and synthetic
oestrogens. However, data about oestrogen's effects on haemostasis in rodents is very …

Objective Controversies still persist concerning hormone replacement therapy (HRT) and its
effects upon blood coagulation and fibrinolysis. This study was carried out to evaluate …

Estrogens have been associated with thromboembolic events. Our group has described the
anticoagulant effect of 17β-aminoestrogens in rodents, potentially new alternative estrogenic …

Recent data has shown that hormone therapy (HT) increases the risk of cardiovascular and
thromboembolic disease, particularly in users of oral HT. Phytoestrogens are popular …