[HTML][HTML] Pharmacological, neurochemical, and behavioral mechanisms underlying the anxiolytic-and antidepressant-like effects of flavonoid chrysin

JF Rodríguez-Landa, LJ German-Ponciano… - Molecules, 2022 - mdpi.com
Chrysin (5, 7-dihydroxyflavone) is a flavonoid isolated from plants, such as Passiflora
coerulea, Passiflora incarnata, and Matricaria chamomilla. This natural molecule exerts …

[HTML][HTML] Neurochemical factors associated with the antidepressant-like effect of flavonoid chrysin in chronically stressed mice

C Borges Filho, CR Jesse, F Donato… - European Journal of …, 2016 - Elsevier
Chrysin is a flavonoid which is found in bee propolis, honey and various plants.
Antidepressant-like effect of chrysin in chronically stressed mice was previously …

Differential effects of acute and chronic treatment with the flavonoid chrysin on anxiety-like behavior and Fos immunoreactivity in the lateral septal nucleus in rats

LJ Germán-Ponciano, A Puga-Olguín… - Acta …, 2020 - hrcak.srce.hr
Sažetak The aim of this study was to compare the effects of acute (a single injection) and
chronic (21 consecutive days) treatments with chrysin 2, 4, and 8 umol kg–1 on anxiety-like …

Neuroprotective effects of chrysin: From chemistry to medicine

SF Nabavi, N Braidy, S Habtemariam, IE Orhan… - Neurochemistry …, 2015 - Elsevier
Abstract The World Health Organization estimated that the proportion of older people (over
60 years) will increase from 11% to 22% during next 40 years throughout the world. With …

[HTML][HTML] Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice

C Borges Filho, CR Jesse, F Donato… - Chemico-Biological …, 2016 - Elsevier
Chrysin is a natural flavonoid which is found in bee propolis, honey and various plants, and
antidepressant-like effect of chrysin in chronically stressed mice was previously …

Lycopene and chrysin through mitigation of neuroinflammation and oxidative stress exerted antidepressant effects in clonidine-induced depression-like behavior in …

EN Abd Al Haleem, HI Ahmed… - Journal of Dietary …, 2023 - Taylor & Francis
Depression is a severely debilitating psychiatric disorder that influences more than 15% of
the population worldwide. It has been demonstrated that it is associated with a high risk of …

[HTML][HTML] Anxiolytic-like effect of quercetin possibly through GABA receptor interaction pathway: In vivo and in silico studies

MS Islam, R Hossain, T Ahmed, MM Rahaman… - Molecules, 2022 - mdpi.com
Scientific evidence suggests that quercetin (QUR) has anxiolytic-like effects in experimental
animals. However, the mechanism of action responsible for its anxiolytic-like effects is yet to …

[HTML][HTML] An updated review on the versatile role of chrysin in neurological diseases: Chemistry, pharmacology, and drug delivery approaches

M Talebi, M Talebi, T Farkhondeh… - Biomedicine & …, 2021 - Elsevier
Neurological diseases are responsible for a large number of morbidities and mortalities in
the world. Flavonoids are phytochemicals that possess various health-promoting impacts …

[HTML][HTML] Neuroprotective potential of chrysin: Mechanistic insights and therapeutic potential for neurological disorders

A Mishra, PS Mishra, R Bandopadhyay, N Khurana… - Molecules, 2021 - mdpi.com
Chrysin, a herbal bioactive molecule, exerts a plethora of pharmacological effects, including
anti-oxidant, anti-inflammatory, neuroprotective, and anti-cancer. A growing body of …

Flavonoids as therapeutic candidates for emotional disorders such as anxiety and depression

YH Ko, SK Kim, SY Lee, CG Jang - Archives of pharmacal research, 2020 - Springer
Emotional disorders such as anxiety and depression are widespread psychological
diseases that affect up to 20% of the world's population. There are many approaches to the …