Antileishmanial activity of lignans, neolignans, and other plant phenols

J Pospíšil, D Konrádová, M Strnad - Progress in the Chemistry of Organic …, 2021 - Springer
Secondary metabolites (SM) from organisms have served medicinal chemists over the past
two centuries as an almost inexhaustible pool of new drugs, drug-like skeletons, and …

Selected Natural and Synthetic Phenolic Compounds with Antileishmanial Activity: A Five-year Review

A Rojas de Arias, E Pandolfi… - Current Bioactive …, 2012 - ingentaconnect.com
Leishmaniasis is among the neglected diseases that represent 90% of the world burden of
morbidity. According to the WHO, there are 12 million people, mostly deeply impoverished …

[PDF][PDF] Selected natural and synthetic phenolic compounds with antileishmanial activity: a five-year review

AR De Arias, E Pandolfi, MC Celeste Vega… - Curr Bioact …, 2012 - academia.edu
Leishmaniasis is among the neglected diseases that represent 90% of the world burden of
morbidity. According to the WHO, there are 12 million people, mostly deeply impoverished …

In vitro screening of natural product-based compounds for leishmanicidal activity

S Tandon, M Puri, Y Bharath, UM Choudhury… - Journal of Parasitic …, 2023 - Springer
Leishmaniasis is one of the major parasitic diseases, caused by obligate intracellular
protozoa Leishmania, having high mortality as well as morbidity rate. As there is no human …

Lignans and neolignans as lead compounds

S Apers, A Vlietinck, L Pieters - Phytochemistry Reviews, 2003 - Springer
Many lignans and neolignans have served as lead compounds for the development of new
drugs. Perhaps the best known example is podophyllotoxin, an antimitotic compound that …

Antileishmanial Activity of Natural Diterpenoids: A Comprehensive Review

F Mirzania, J Ghasemian Yadegari… - Current Organic …, 2023 - ingentaconnect.com
Infections that occur by protozoa are a chief universal issue for health, with wide endemicity
in the involved areas. In the absence of a vaccine, there is an immediate requirement for …

Phytochemicals with antileishmanial activity: prospective drug targets

S Hazra, S Ghosh, B Hazra - Studies in natural products chemistry, 2017 - Elsevier
Protozoan parasites are among the most common causative agents of some of the major
tropical diseases occurring in both humans and domestic animals, leading to enormous loss …

Plant-derived natural products for the treatment of Leishmaniasis

J Rohloff, A Hymete, Y Tariku - Studies in Natural Products Chemistry, 2013 - Elsevier
Leishmaniasis is a vector-borne parasitic disease caused by protozoan parasites belonging
to the family Trypanosomatidae and genus Leishmania. The disease prevails in 88 …

In vivo antileishmanial activity of plant-based secondary metabolites

LFD Passero, MD Laurenti, G Santos-Gomes… - … Resistance with Herbal …, 2013 - Elsevier
Leishmaniasis is an infectious disease caused by parasites belonging to the Leishmania
genus. This disease has a prevalence that exceeds 12 million, and approximately 350 …

[PDF][PDF] Antileishmanial activity of medicinal plants from Africa: a review

A Et-Touys, A Bouyahya, H Fellah… - Asian Pacific Journal …, 2017 - academia.edu
Leishmaniasis is regarded as a major public health problem, causing significant morbidity
and mortality rates in Africa, Asia and Latin America. The disease currently threatens about …