Enrichment of putatively damaging rare variants in the DYX2 locus and the reading-related genes CCDC136 and FLNC

AK Adams, SD Smith, DT Truong, EG Willcutt… - Human genetics, 2017 - Springer
Eleven loci with prior evidence for association with reading and language phenotypes were
sequenced in 96 unrelated subjects with significant impairment in reading performance …

A family‐based association analysis and meta‐analysis of the reading disabilities candidate gene DYX1C1

C Tran, F Gagnon, KG Wigg, Y Feng… - American Journal of …, 2013 - Wiley Online Library
Reading disabilities (RD) have a significant genetic basis and have shown linkage to
multiple regions including chromosome 15q. Dyslexia susceptibility 1 candidate gene 1 …

The genetics of reading disability

TL Petryshen, DL Pauls - Current psychiatry reports, 2009 - Springer
Genetic factors contribute substantially to the development of reading disability (RD). Family
linkage studies have implicated many chromosomal regions containing RD susceptibility …

Evaluation of candidate genes for DYX1 and DYX2 in families with dyslexia

Z Brkanac, NH Chapman… - American Journal of …, 2007 - Wiley Online Library
Dyslexia is a common heterogeneous disorder with a significant genetic component.
Multiple studies have replicated the evidence for linkage between variously defined …

The KIAA0319-Like (KIAA0319L) Gene on Chromosome 1p34 as a Candidate for Reading Disabilities

JM Couto, L Gomez, K Wigg, T Cate-Carter… - Journal of …, 2008 - Taylor & Francis
A locus on chromosome 1p34-36 (DYX8) has been linked to developmental dyslexia or
reading disabilities (RD) in three independent samples. In the current study, we investigated …

Association of short‐term memory with a variant within DYX1C1 in developmental dyslexia

C Marino, A Citterio, R Giorda, A Facoetti… - Genes, Brain and …, 2007 - Wiley Online Library
A substantial genetic contribution in the etiology of developmental dyslexia (DD) has been
well documented with independent groups reporting a susceptibility locus on chromosome …

DCDC2 is associated with reading disability and modulates neuronal development in the brain

H Meng, SD Smith, K Hager, M Held… - Proceedings of the …, 2005 - National Acad Sciences
DYX2 on 6p22 is the most replicated reading disability (RD) locus. By saturating a
previously identified peak of association with single nucleotide polymorphism markers, we …

Variants in the DYX2 locus are associated with altered brain activation in reading-related brain regions in subjects with reading disability

N Cope, JD Eicher, H Meng, CJ Gibson, K Hager… - Neuroimage, 2012 - Elsevier
Reading disability (RD) is a complex genetic disorder with unknown etiology. Genes on
chromosome 6p22, including DCDC2, KIAA0319, and TTRAP, have been identified as RD …

Characterization of the DYX2 locus on chromosome 6p22 with reading disability, language impairment, and IQ

JD Eicher, NR Powers, LL Miller, KL Mueller… - Human Genetics, 2014 - Springer
Reading disability (RD) and language impairment (LI) are common neurodevelopmental
disorders with moderately strong genetic components and lifelong implications. RD and LI …

Dyslexia and DYX1C1: deficits in reading and spelling associated with a missense mutation

TC Bates, PA Lind, M Luciano, GW Montgomery… - Molecular …, 2010 - nature.com
The status of DYX1C1 (C15q21. 3) as a susceptibility gene for dyslexia is unclear. We report
the association of this gene with reading and spelling ability in a sample of adolescent twins …