Biocompatible polymer nanoformulation to improve the release and safety of a drug mimic molecule detectable via ICP-MS

R Ferrari, L Talamini, MB Violatto… - Molecular …, 2017 - ACS Publications
Fluorescent poly (ε-caprolactone)-based nanoparticles (NPs) have been synthesized and
successfully loaded with a titanium organometallic compound as a mimic of a water …

Co-encapsulation of magnetic nanoparticles and cisplatin within biocompatible polymers as multifunctional nanoplatforms: synthesis, characterization, and in vitro …

J Ibarra, D Encinas, M Blanco, S Barbosa… - Materials Research …, 2018 - iopscience.iop.org
In this work, we report the synthesis, characterization and biological evaluation of a
multifunctional hybrid biocompatible nanoplatform consisting of a biodegradable poly (lactic …

Fluorescence imaging of cancer tissue based on metal-free polymeric nanoparticles–a review

A Vollrath, S Schubert, US Schubert - Journal of Materials Chemistry B, 2013 - pubs.rsc.org
The utilization of fluorescent nanoparticles (FNPs), which consist of organic fluorophores
embedded into a polymer matrix, seems to be a promising concept for in vivo cancer …

Applications of Biodegradable Polymers in the Encapsulation of Anticancer Metal Complexes

M Redrado, Z Xiao, K Upitak, BT Doan… - Advanced Functional …, 2024 - Wiley Online Library
Metal complexes have recently attracted a lot of attention, particularly as anticancer and
antibacterial agents, owing to their versatile mechanisms and easily tunable characteristics …

Drug-Initiated Synthesis of Heterotelechelic Polymer Prodrug Nanoparticles for in Vivo Imaging and Cancer Cell Targeting

D Vinciguerra, A Degrassi, L Mancini, S Mura… - …, 2019 - ACS Publications
“Drug-initiated” nitroxide-mediated synthesis of two well-defined, heterotelechelic polymer
prodrugs (M n= 1960–5260 g· mol–1, Đ= 1.31–1.37) was performed by using the newly …

Engineered polymer-based nanomaterials for diagnostic, therapeutic and theranostic applications

O Ilaria Parisi, L Scrivano… - Mini reviews in …, 2016 - ingentaconnect.com
Nanomedicine can be defined as the medical application of molecular nanotechnology and
it plays a key role and pharmaceutical research and development, especially related to …

Polymeric nanosystems applied for metal-based drugs and photosensitizers delivery: the state of the art and recent advancements

KCF Dantas, JS Rosário, PP Silva-Caldeira - Pharmaceutics, 2022 - mdpi.com
Nanotechnology-based approaches for targeting the delivery and controlled release of
metal-based therapeutic agents have revealed significant potential as tools for enhancing …

Biodegradable core-shell nanoassemblies for the delivery of docetaxel and Zn (II)-phthalocyanine inspired by combination therapy for cancer

C Conte, F Ungaro, G Maglio, P Tirino… - Journal of Controlled …, 2013 - Elsevier
Combination therapies for cancer aim to exploit either additive or synergistic effects arising
from the action of two species with the final goal to maximize the therapeutic efficacy. In this …

Labeled nanoparticles based on pharmaceutical EUDRAGIT® S 100 polymers

A Vollrath, S Schubert, N Windhab… - Macromolecular …, 2010 - Wiley Online Library
The pharmaceutically important polymer P (MAA–r–MMA) 1: 2 (EUDRAGIT® S100) was
investigated concerning its behavior to form nanoparticles via nanoprecipitation. The …

Multiplexed analysis of the cellular uptake of polymeric nanocarriers

DK Agrohia, P Wu, U Huynh, S Thayumanavan… - Analytical …, 2022 - ACS Publications
Polymeric nanocarriers (PNCs) are versatile drug delivery vehicles capable of delivering a
variety of therapeutics. Quantitatively monitoring their uptake in biological systems is …