Vascular endothelial growth factor (VEGF) is a key mediator of angiogenesis, whose effect
on cancer growth and development is well characterized. Alternative splicing of VEGF leads …

Angiogenesis, the formation of new blood vessels from existing vasculature, is important in
tumor growth and metastasis. A key regulator of angiogenesis is vascular endothelial growth …

Background Vascular endothelial growth factor (VEGF) is known to be a potent promoter of
angiogenesis under both physiological and pathological conditions. Given its role in …

Background Vascular endothelial growth factor (VEGF) is a potent regulator of
angiogenesis, and its role in cancer biology has been widely studied. Many cancer …

Plasma membrane‐localized vascular endothelial growth factor receptors (VEGFR) play a
critical role in transducing VEGF signaling toward pro and antiangiogenic outcomes and …

VEGF is the best characterized mediator of tumor angiogenesis. Anti-VEGF agents have
recently demonstrated impressive efficacy in human cancer trials, but the optimal dosing of …

Tumors require nutrients and oxygen in order to grow, and new blood vessels, formed by the
process of angiogenesis, provide these substrates. The key mediator of angiogenesis is …

Vascular endothelial growth factor (VEGF) is a primary stimulant of the vascularization of
solid tumors and has therefore been the focus of intense research aimed at blocking its …

Angiogenesis (neovascularization) plays a crucial role in a variety of physiological and
pathological conditions including cancer, cardiovascular disease, and wound healing …

Vascular endothelial growth factor (VEGF) is one of the most potent cytokines targeted in
antiangiogenic therapies. Bevacizumab, a recombinant humanized monoclonal antibody to …