Treat-to-target is used to manage a variety of different chronic diseases, including diabetes
mellitus, hyperlipidemia, hypertension, and gouty as well as rheumatoid arthritis. The …

Abstract Purpose of Review Treat-to-target (goal-directed therapy) has been proposed as a
strategy to assist clinicians in selecting the most appropriate initial treatment for osteoporosis …

ABSTRACT The American Society for Bone and Mineral Research and the United States
National Osteoporosis Foundation (NOF) formed a working group to develop principles of …

Monitoring treatment effects can inform both the physician and patient whether the
medication has achieved its anticipated targets. There are several variances between …

Abstract Treat-to-target (TTT) for osteoporosis is a concept for individualizing patient
treatment decisions that focuses on achieving an acceptable level of fracture risk rather than …

The management of osteoporosis is changing—for the better. Perhaps the most progressive
recent step has been the assessment of fracture risk using clinical risk factors through tools …

Decision in starting and modulating the treatment of osteoporosis is being done by bone
mineral density prevalent fractures, bone turnover markers, and other clinical indicators …

The preferred outcome of treating patients with osteoporosis is no fracture. All approved
treatments for osteoporosis can improve bone mineral density, increase bone strength, and …

Drug treatment for osteoporosis typically begins with an oral bisphosphonate, regardless of
initial bone mineral density (BMD) or fracture risk, and decisions to continue or change …

Objectives: Current clinical practice guidelines identify patients at high risk for fracture who
are likely to benefit from pharmacological therapy and suggest ways to monitor for …