Regulatory T cells (Tregs) are critical mediators of peripheral immune tolerance. Tregs
suppress immune activation against self-antigens and are the focus of cell-based therapies …

Over the past few decades, regulatory T cell (Treg) therapy has gained traction for the
treatment of autoimmunity, transplant rejection, and other inflammatory diseases. A …

Regulatory T cell (Treg)-based therapeutics are receiving increased attention for their
potential to treat autoimmune disease and prevent transplant rejection. Adoptively …

Regulatory T cell therapy has shown promise in treating autoimmune disorders, transplant
rejection and graft-versus-host disease in early clinical trials. However, efficient …

In recent years, the exploration of regulatory T cell (Treg)-based cellular therapy has
become an attractive strategy to ameliorate inflammation and autoimmunity in various …

T cell-mediated immune rejection remains a barrier to successful transplantation. Polymer-
based bioengineering of cells may provide an effective means of preventing allorecognition …

The concept of regulatory T cell (Treg)-based immunotherapy has enormous potential for
facilitating tolerance in autoimmunity and transplantation. Clinical translation of Treg cell …

The cytokine milieu is critical for orchestration of lineage development towards effector T cell
(Teff) or regulatory T cell (Treg) subsets implicated in the progression of cancer and …

The absence of regulatory T cells (Treg) is a hallmark for a wide variety of disorders such as
autoimmunity, dermatitis, periodontitis and even transplant rejection. A potential treatment …

Highlights•'Next generation'Treg cell therapy products will use genetic engineering to
enhance function.•Methods to scale up Treg cell therapy products depend on cell source …