Background information. The gap junction protein, Cx43 (connexin 43), has been implicated
in the aetiology of osteoarthritis. Studies have revealed that the size and number of gap …

Chondrocytes in cartilage and bone cells population express connexin43 (Cx43) and gap
junction intercellular communication (GJIC) is essential to synchronize cells for coordinated …

Connexin 43 (Cx43) exerts pivotal functions in articular chondrocytes (CH). It is involved in
the communication among cells and between cells and the extracellular environment, and it …

Background Recent work has shown that the gap junction protein connexin43 (Cx43) is
upregulated in cells of the joint during osteoarthritis (OA). Here we examined if the OA …

The distribution, expression, and functionality of gap junctions was examined in bovine
chondrocytes (BCs) isolated from mature articular cartilage. BC cells displayed …

The gap junction protein, connexin43 (Cx43), plays an important role in skeletal biology.
Previously, we have shown that Cx43 can enhance the signaling and transcriptional …

Gap junction intercellular communication (GJIC) allows the transfer of material, message
and energy between cells, which influences cell behaviors including cell proliferation …

Summary Objective Connexin (Cx) 43 hemichannels play a role in mechanotransduction.
This study was undertaken in order to determine if Cx43 hemichannels were activated in rat …

Osteoarthritis (OA) is the most common joint disease and involves progressive degeneration
of articular cartilage. The aim of this study was to investigate if chondrocytes from human …

We have previously reported that articular chondrocytes in tissue contain long cytoplasmic
arms that physically connect two distant cells. Cell-to-cell communication occurs through …