Connexins (Cx) are primary components of gap junctions that selectively allow molecules to
be exchanged between adjacent cells, regulating multiple cellular functions. Along with their …

Defects in craniofacial tissues, resulting from trauma, congenital abnormalities, oncologic
resection or progressive deforming diseases, may result in aesthetic deformity, pain and …

Background This study was designed to explore the mechanisms through which
chondrocytes regulated endothelial cell migration and angiogenesis in osteoarthritis (OA) …

Osteoarthritis (OA) is a whole joint disease characterized by an important remodeling of the
osteochondral junction. It includes cartilage mineralization due to chondrocyte hypertrophic …

Shaping of the skeleton (modeling) and its maintenance throughout life (remodeling) require
coordinated activity among bone forming (osteoblasts) and resorbing cells (osteoclasts) and …

The molecular mechanisms regulating skeletal muscle regeneration and differentiation are
not well understood. We analyzed the expression of connexins (Cxs) 40, 43 and 45 in …

Previous studies showed that intercellular communication by gap junctions has a role in
bone formation. The main connexin involved in the development, differentiation, and …

Objective Transforming growth factor-β (TGF-β) is an important homeostatic regulator of
cartilage. In contrast, interleukin-6 (IL-6) is a pro-inflammatory cytokine implicated in …

Objective—Vascular disease alters and reduces connexin expression and a reduction in
connexin 43 (Cx43) expression diminishes the extent of atherosclerosis observed in a high …

Gap junctions formed by connexins (Cx) play an important role in transmitting signals
between bone cells such as osteoblasts and osteoclasts, cells responsible for bone …