Purpose Classical Hodgkin's lymphoma (CHL) is characterized by Hodgkin's and Reed-
Sternberg (H-RS) cells, most of which are derived from germinal-center B cells …

Background Classical Hodgkin's lymphoma is characterized by Hodgkin and Reed
Sternberg cells, which are of B-cell origin in many cases. We recently highlighted the …

The lymphocyte-depleted type (LD) is a morphological subtype of classical Hodgkin
lymphoma (CHL), but its rarity and heterogeneous morphological character makes a definite …

Abstract Hodgkin/Reed-Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL) rarely
express T-cell-associated antigens (TCA), but the clinical significance of this finding is …

Abstract Hodgkin's and Reed–Sternberg cells of classical Hodgkin's lymphoma are primarily
of B-cell origin, although there are instances of T-cell antigen expression suggesting T-cell …

Purpose The neoplastic Hodgkin Reed-Sternberg (HRS) cells in classical Hodgkin's
lymphoma (cHL) are derived from B cells. The frequency of HLA class II downregulation and …

Abstract Purpose: Recent studies of Hodgkin's lymphoma (HL) have suggested that the
presence of regulatory T cells in the reactive background may explain the inhibition of the …

The existence, diagnostic features, and the biological and clinical relevance of lymphocyte-
rich classical Hodgkin's lymphoma remain controversial. A comparative marker analysis of …

Purpose To investigate the clinical characteristics and treatment outcome of patients with
lymphocyte-depleted classical Hodgkin's lymphoma (LDCHL) compared with other …

Abstract The World Health Organization has acknowledged the malignant nature of classical
Hodgkin lymphoma (cHL), which encompasses four histological subtypes. The diagnosis of …