ER and HER2 are critical drivers of breast cancer biology and can interact when co-
expressed, but less data describe the impact of ER/HER2 co-expression on clinical disease …

Background Breast cancer comprises several molecular subtypes with different prognoses
and possibly different etiology. Reproductive and hormonal factors are associated with …

Male breast cancer (MBC) is rare and poorly characterized. Like the female counterpart,
most MBCs are hormonally driven, but relapse after hormonal treatment is also noted. The …

Importance There has been little consideration of genomic risk of recurrence by breast
cancer subtype despite evidence of racial disparities in breast cancer outcomes. Objective …

Background Breast cancers lacking the estrogen receptor (ER) can be distinguished from
other breast cancers on the basis of poor prognosis, high grade, distinctive histopathology …

Sex steroid hormone signaling is critical in the development of breast cancers, although the
role of the androgen receptor remains unclear. This study evaluated androgen receptor (AR) …

The aim of this study is to evaluate the prognostic values of some biological parameters in a
population based series of female breast cancer patients. Through the Tuscan Cancer …

Background Oestrogen receptor (ER) positive breast cancer (BC) patients are eligible for
endocrine therapy (ET), regardless of ER immunohistochemical expression level. There is a …

Breast cancer represents a heterogenous group of diseases with different molecular and
clinical features [1]. Clinical assessment of estrogen receptor (ER), progesterone receptor …

Background It is unknown whether ER (-)/PR (+) breast cancer is an independent breast
cancer subtype, how it differs from other subtypes, and what its significance is regarding …