Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics
Atherosclerosis, the principal cause of cardiovascular death worldwide, is a pathological
disease characterized by fibro-proliferation, chronic inflammation, lipid accumulation, and …
disease characterized by fibro-proliferation, chronic inflammation, lipid accumulation, and …
Atherosclerosis is an epigenetic disease
Atherosclerosis is a chronic inflammatory and lipid-depository disease that eventually leads
to acute cardiovascular events. Emerging evidence supports that epigenetic processes such …
to acute cardiovascular events. Emerging evidence supports that epigenetic processes such …
Epigenetics of atherosclerosis: emerging mechanisms and methods
Atherosclerosis is a vascular pathology characterized by inflammation and plaque build-up
within arterial vessel walls. Vessel occlusion, often occurring after plaque rupture, can result …
within arterial vessel walls. Vessel occlusion, often occurring after plaque rupture, can result …
Epigenetics and vascular diseases
Cardiovascular disease remains the number one cause of death and disability worldwide
despite significant improvements in diagnosis, prevention, and early intervention efforts …
despite significant improvements in diagnosis, prevention, and early intervention efforts …
Potential epigenetic therapeutics for atherosclerosis treatment
I Nicorescu, GM Dallinga, MPJ de Winther, ESG Stroes… - Atherosclerosis, 2019 - Elsevier
Notwithstanding the intense efforts into the understanding and prevention of cardiovascular
disease (CVD), its complex pathology remains the leading cause of mortality worldwide. The …
disease (CVD), its complex pathology remains the leading cause of mortality worldwide. The …
[HTML][HTML] The key role of DNA methylation and histone acetylation in epigenetics of atherosclerosis
HT Lee, S Oh, H Yoo, YW Kwon - Journal of lipid and …, 2020 - ncbi.nlm.nih.gov
Atherosclerosis, which is the most common chronic disease of the coronary artery,
constitutes a vascular pathology induced by inflammation and plaque accumulation within …
constitutes a vascular pathology induced by inflammation and plaque accumulation within …
Epigenetics and atherosclerosis
MP Turunen, E Aavik, S Ylä-Herttuala - Biochimica et Biophysica Acta (BBA …, 2009 - Elsevier
The contribution of epigenetic mechanisms to cardiovascular diseases remains poorly
understood. Hypomethylation of genomic DNA is present in human atherosclerotic lesions …
understood. Hypomethylation of genomic DNA is present in human atherosclerotic lesions …
Epigenetic reprogramming in atherosclerosis
V Grimaldi, MT Vietri, C Schiano, A Picascia… - Current atherosclerosis …, 2015 - Springer
Recent data support the involvement of epigenetic alterations in the pathogenesis of
atherosclerosis. The most widely investigated epigenetic mechanism is DNA methylation …
atherosclerosis. The most widely investigated epigenetic mechanism is DNA methylation …
Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis
Atherosclerosis is a lipid-driven chronic inflammatory disorder. Monocytes and
macrophages are key immune cells in the development of disease and clinical outcome. It is …
macrophages are key immune cells in the development of disease and clinical outcome. It is …
DNA methylation processes in atherosclerotic plaque
E Aavik, M Babu, S Ylä-Herttuala - Atherosclerosis, 2019 - Elsevier
Underlying mechanisms of cardiovascular diseases (CVD) have been investigated for over
100 years and novel molecular level mechanisms in the pathophysiology are still …
100 years and novel molecular level mechanisms in the pathophysiology are still …