[HTML][HTML] Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials

Y Shi, H Zhang, S Huang, L Yin, F Wang… - … and Targeted Therapy, 2022 - nature.com
Epigenetics is closely related to cardiovascular diseases. Genome-wide linkage and
association analyses and candidate gene approaches illustrate the multigenic complexity of …

Epigenetics in atherosclerosis and inflammation

RJ Wierda, SB Geutskens, JW Jukema… - Journal of cellular …, 2010 - Wiley Online Library
Introduction• Epigenetics explained‐Epigenetic alterations are reversible• Atherosclerosis•
Epigenetics and association with atherosclerosis• Epigenetic regulation of cell activity‐T …

[HTML][HTML] Potential regulatory role of epigenetic RNA methylation in cardiovascular diseases

S Komal, LR Zhang, SN Han - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide,
especially in developing countries. To date, several approaches have been proposed for the …

[HTML][HTML] DNA methylation aberrant in atherosclerosis

Y Dai, D Chen, T Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
Atherosclerosis (AS) is a pathological process involving lipid oxidation, immune system
activation, and endothelial dysfunction. The activated immune system could lead to …

Epigenetics in the vascular endothelium: looking from a different perspective in the epigenomics era

MS Yan, PA Marsden - Arteriosclerosis, thrombosis, and vascular …, 2015 - Am Heart Assoc
Cardiovascular diseases are commonly thought to be complex, non-Mendelian diseases
that are influenced by genetic and environmental factors. A growing body of evidence …

Epigenetic regulation of vascular diseases

A Zarzour, HW Kim, NL Weintraub - … , thrombosis, and vascular …, 2019 - Am Heart Assoc
Epigenetic regulatory mechanisms, encompassing diverse molecular processes including
DNA methylation, histone post-translational modifications, and noncoding RNAs, are …

Cardiovascular epigenetics: from DNA methylation to microRNAs

S Udali, P Guarini, S Moruzzi, SW Choi… - Molecular aspects of …, 2013 - Elsevier
Epigenetic phenomena are defined as heritable mechanisms that establish and maintain
mitotically stable patterns of gene expression without modifying the base sequence of DNA …

[HTML][HTML] Histone methylation and vascular biology

X Wei, X Yi, XH Zhu, DS Jiang - Clinical epigenetics, 2020 - Springer
The vasculature not only transports oxygenated blood, metabolites, and waste products but
also serves as a conduit for hormonal communication between distant tissues. Therefore, it …

Epigenetic changes in diabetes and cardiovascular risk

ST Keating, J Plutzky, A El-Osta - Circulation research, 2016 - Am Heart Assoc
Cardiovascular complications remain the leading causes of morbidity and premature
mortality in patients with diabetes mellitus. Studies in humans and preclinical models …

DNA methylation abnormalities in atherosclerosis

S Tabaei, SS Tabaee - Artificial cells, nanomedicine, and …, 2019 - Taylor & Francis
Atherosclerosis is a complex disease with involvement of intermediate-, large-sized arteries.
Atherosclerosis is characterized by the accumulation of vascular lipids, immune system …