DNA methylation abnormalities in atherosclerosis

S Tabaei, SS Tabaee - Artificial cells, nanomedicine, and …, 2019 - Taylor & Francis
Atherosclerosis is a complex disease with involvement of intermediate-, large-sized arteries.
Atherosclerosis is characterized by the accumulation of vascular lipids, immune system …

[HTML][HTML] DNA methylation and atherosclerosis

C Dong, W Yoon, PJ Goldschmidt-Clermont - The Journal of nutrition, 2002 - Elsevier
DNA methylation is a major epigenetic modification of the genome that has the potential to
silence gene expression. Recently, the role of epigenetic alteration as a distinct and crucial …

Epigenetic-related therapeutic challenges in cardiovascular disease

C Schiano, MT Vietri, V Grimaldi, A Picascia… - Trends in …, 2015 - cell.com
Progress in human genetic and genomic research has led to the identification of genetic
variants associated with specific cardiovascular diseases (CVDs), but the pathogenic …

Aberrant DNA methylation in the pathogenesis of atherosclerosis

Z Hai, W Zuo - Clinica Chimica Acta, 2016 - Elsevier
Atherosclerosis, a multifactorial disease of large-and intermediate-sized arteries, is
characterized by the accumulation of lipids and the proliferation of arterial smooth muscle …

On the epigenetics of vascular regulation and disease

C Schleithoff, S Voelter-Mahlknecht, IN Dahmke… - Clinical …, 2012 - Springer
Consolidated knowledge is accumulating as to the role of epigenetic regulatory mechanisms
in the physiology of vascular development and vascular tone as well as in the pathogenesis …

[HTML][HTML] Molecular mechanisms and genetic regulation in atherosclerosis

AO Jackson, MA Regine, C Subrata, S Long - IJC heart & vasculature, 2018 - Elsevier
Atherosclerosis (AS) manifested by lipid accumulation, extracellular matrix protein
deposition, and calcification in the intima and media of the large to medium size arteries …

Epigenetic Modifications and Non-Coding RNA in Diabetes-Mellitus-Induced Coronary Artery Disease: Pathophysiological Link and New Therapeutic Frontiers

FR Prandi, D Lecis, F Illuminato, M Milite… - International Journal of …, 2022 - mdpi.com
Diabetes mellitus (DM) is a glucose metabolism disorder characterized by chronic
hyperglycemia resulting from a deficit of insulin production and/or action. DM affects more …

DNA modifications in atherosclerosis: from the past to the future

A Borghini, T Cervelli, A Galli, MG Andreassi - Atherosclerosis, 2013 - Elsevier
The role of DNA damage in the pathogenesis of atherosclerosis has been extensively
investigated in recent decades. There is now clear that oxidative stress is an important …

The impact of epigenetics on cardiovascular disease

D Prasher, SC Greenway… - Biochemistry and Cell …, 2020 - cdnsciencepub.com
Mortality and morbidity from cardiovascular diseases (CVDs) represents a huge burden to
society. It is recognized that environmental factors and individual lifestyles play important …

Diverse epigenetic regulations of macrophages in atherosclerosis

H Yang, Y Sun, Q Li, F Jin, Y Dai - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Emerging research on epigenetics has resulted in many novel discoveries in atherosclerosis
(AS), an inflammaging-associated disease characterized by chronic inflammation primarily …