Midazolam, a short-acting benzodiazepine, is widely used to alleviate patient anxiety,
enhance compliance, and aid in anesthesia. While its side effects are typically dose …

Objectives: Summarize the mechanism of action of midazolam. Describe the various
indications where midazolam can be effective. Review the adverse event profile of …

Aim To compare the clearance of midazolam and its metabolites in critically ill paediatric and
adult patients. Method A prospective study conducted in paediatric and adult intensive care …

Objective We investigated the pharmacologic properties of midazolam with special regard to
age using the electroencephalogram (EEG) as a measure of the hypnotic‐sedative effect …

Background Midazolam, a benzodiazepine, is finding expanded use in neonatal intensive
care units. We studied the pharmacokinetics and metabolism of midazolam after a single …

Benzodiazepines are commonly used to provide sedation for infants and children
undergoing intensive care or diagnostic and therapeutic procedures in a variety of clinical …

A variety of developmental changes is of influence on the pharmacokinetics and
pharmacodynamics of midazolam in neonatal and pediatric intensive care patients …

Objective To describe the pharmacokinetics of midazolam, a water‐soluble benzodiazepine
with a short half‐life, in critically ill neonates. Hypothesis Midazolam clearance is reduced in …

Although midazolam is a frequently used sedative in neonatal intensive care units, its use in
preterm neonates has been off‐label. Recently, a new dosing advice for midazolam for …

The first‐dose pharmacokinetics of midazolam and its primary α‐hydroxy metabolite were
studied after single‐dose administration. Eligible study patients were enrolled into one of …