Introduction Oxygen-induced retinopathy is a type of retinal pathological neovascularization
(NV) disease that leads to vision loss and translates to a significant societal cost. Anti …

Retinal neovascularization (RNV) is a principal cause of visual impairment and blindness
worldwide. The present study aimed to investigate how oxidative stress, autophagy and …

Aberrant neovascularization is the most common feature in retinopathy of prematurity (ROP),
which leads to the retinal detachment and visual defects in neonates with a low gestational …

Objective: Retinal neovascularization is an iconic change in retinopathies. Vascular
Endothelial Growth Factor (VEGF) and α-crystallins have been identified to mediate the …

Background Retinal neovascularization (NV) is a major cause of blindness associated with
ischemic retinal disorders. Our study was focused on evaluating the inhibitory effect of …

AIM To investigate the role of CCR7/p-ERK1/2/VEGF signaling in the mouse model of
oxygen-induced retinopathy (OIR). METHODS Neonatal C57BL/6J mice were evenly …

Purpose.: Neovascularization occurs in response to tissue ischemia and growth factor
stimulation. In ischemic retinopathies, however, new vessels fail to restore the hypoxic …

In retinopathy of prematurity (ROP), outer deep vascular plexus (oDVP) was the emerging
field, and the mechanisms of photoreceptor dysfunction remained to be explored. ODVP and …

AIM To explore an efficient, practical and objective quantitative method to evaluate the
retinal neovascularization in mouse model of oxygen induced retinopathy (OIR). METHODS …

Purpose To establish a quantifying model of retinal neovascularization suitable for
examining pathogenesis and therapeutic intervention for the retinal neovascularization …