Pseudomonas aeruginosa: all roads lead to resistance

EBM Breidenstein, C de la Fuente-Núñez… - Trends in …, 2011 - cell.com
Pseudomonas aeruginosa is often resistant to multiple antibiotics and consequently has
joined the ranks of 'superbugs' due to its enormous capacity to engender resistance. It …

[HTML][HTML] The many antibiotic resistance and tolerance strategies of Pseudomonas aeruginosa

D Sindeldecker, P Stoodley - Biofilm, 2021 - Elsevier
Pseudomonas aeruginosa is a bacterial pathogen associated with a wide range of infections
and utilizes several strategies to establish and maintain infection including biofilm …

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and impact on treatment

REW Hancock, DP Speert - Drug resistance updates, 2000 - Elsevier
Pseudomonas aeruginosa continues to be a major cause of infections in Western society, in
part because of its high intrinsic resistance to antibiotics. It has been demonstrated that this …

Pseudomonas Aeruginosa: Arsenal of Resistance Mechanisms, Decades of Changing Resistance Profiles, and Future Antimicrobial Therapies

ME El Zowalaty, AA Al Thani, TJ Webster… - Future …, 2015 - Taylor & Francis
Antimicrobial resistance is one of the most serious public health issues facing humans since
the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of …

Genomewide Identification of Genetic Determinants of Antimicrobial Drug Resistance in Pseudomonas aeruginosa

A Dötsch, T Becker, C Pommerenke… - Antimicrobial agents …, 2009 - Am Soc Microbiol
The emergence of antimicrobial drug resistance is of enormous public concern due to the
increased risk of delayed treatment of infections, the increased length of hospital stays, the …

[HTML][HTML] Mechanisms of antibiotic resistance in Pseudomonas aeruginosa biofilms

M Fernández-Billón, AE Llambías-Cabot… - Biofilm, 2023 - Elsevier
Pseudomonas aeruginosa is a major cause of life-threatening acute infections and life-long
lasting chronic infections. The characteristic biofilm mode of life in P. aeruginosa chronic …

[HTML][HTML] The Versatile Mutational Resistome of Pseudomonas aeruginosa

C López-Causapé, G Cabot… - Frontiers in …, 2018 - frontiersin.org
One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for
developing antimicrobial resistance to nearly all available antipseudomonal agents through …

Pseudomonas aeruginosa: a clinical and genomics update

AC Pelegrin, M Palmieri, C Mirande… - FEMS Microbiology …, 2021 - academic.oup.com
Antimicrobial resistance (AMR) has become a global medical priority that needs urgent
resolution. Pseudomonas aeruginosa is a versatile, adaptable bacterial species with …

[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

Z Pang, R Raudonis, BR Glick, TJ Lin, Z Cheng - Biotechnology advances, 2019 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …

[HTML][HTML] The neglected intrinsic resistome of bacterial pathogens

A Fajardo, N Martínez-Martín, M Mercadillo, JC Galán… - PloS one, 2008 - journals.plos.org
Bacteria with intrinsic resistance to antibiotics are a worrisome health problem. It is widely
believed that intrinsic antibiotic resistance of bacterial pathogens is mainly the consequence …