Objective—Because of the large variation in oxidizing procedures and susceptibility to
oxidation of low-density lipoprotein (LDL) and the lack in quantification of LDL oxidation, the …

Objectives Platelets generate oxidized LDL (ox-LDL) via NOX2-derived oxidative stress. We
investigated if once generated by activated platelets ox-LDL can propagate platelet …

Interactions between altered lipoproteins and platelets may be important in atherosclerosis
lesion formation and thrombosis. The aims of this study were to compare the effects of …

Objective—The interaction of platelets with low density lipoprotein (LDL) contributes to the
development of cardiovascular disease. Platelets are activated by native LDL (nLDL) …

Native LDL and LDL oxidized under various conditions were compared in terms of their
ability to activate platelets. Native LDL did not induce platelet shape change or aggregation …

Low-density lipoproteins (LDL) have been various reported to induce platelet aggregation
independently and/or sensitise platelets to other agonists. In these earlier studies the extent …

Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic
mediators that play a crucial role in cardiovascular and inflammatory diseases. Mildly …

Dyslipidaemia leads to proatherogenic oxidative lipid stress that promotes vascular
inflammation and thrombosis, the pathologies that underpin myocardial infarction, stroke …

Low-density lipoproteins (LDL) are thought to influence directly the sensitivity of platelets,
but this may only be the case when the LDL are modified by oxidation. In diabetes, LDL are …

Conflicting reports exist about the effects of mildly or extensively oxidized low density
lipoproteins (LDLs) on the reactivity of human platelets. This platelet response is mainly …