Population Genomics of Chlamydia trachomatis: Insights on Drift, Selection, Recombination, and Population Structure
The large number of sexually transmitted diseases and ocular trachoma cases that are
caused globally each year by Chlamydia trachomatis has made this organism a World …
caused globally each year by Chlamydia trachomatis has made this organism a World …
Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing
Chlamydia trachomatis is responsible for both trachoma and sexually transmitted infections,
causing substantial morbidity and economic cost globally. Despite this, our knowledge of its …
causing substantial morbidity and economic cost globally. Despite this, our knowledge of its …
Interplay of recombination and selection in the genomes of Chlamydia trachomatis
Background Chlamydia trachomatis is an obligate intracellular bacterial parasite, which
causes several severe and debilitating diseases in humans. This study uses comparative …
causes several severe and debilitating diseases in humans. This study uses comparative …
Genomic features beyond Chlamydia trachomatis phenotypes: what do we think we know?
A Nunes, MJ Borrego, JP Gomes - Infection, Genetics and Evolution, 2013 - Elsevier
The obligate intracellular pathogen Chlamydia trachomatis is the causative agent of the
blinding trachoma and the world's leading cause of bacterial sexually transmitted infections …
blinding trachoma and the world's leading cause of bacterial sexually transmitted infections …
Chlamydia trachomatisdiversity viewed as a tissue-specific coevolutionary arms race
Background The genomes of pathogens are thought to have evolved under selective
pressure provided by the host in a coevolutionary arms race (the'Red Queen's Hypothesis') …
pressure provided by the host in a coevolutionary arms race (the'Red Queen's Hypothesis') …
Evolution of Chlamydia trachomatis diversity occurs by widespread interstrain recombination involving hotspots
Chlamydia trachomatis is an obligate intracellular bacterium of major public health
significance, infecting over one-tenth of the world's population and causing blindness and …
significance, infecting over one-tenth of the world's population and causing blindness and …
Evolution, phylogeny, and molecular epidemiology of Chlamydia
A Nunes, JP Gomes - Infection, Genetics and Evolution, 2014 - Elsevier
The Chlamydiaceae are a family of obligate intracellular bacteria characterized by a unique
biphasic developmental cycle. It encompasses the single genus Chlamydia, which involves …
biphasic developmental cycle. It encompasses the single genus Chlamydia, which involves …
Effect of long-term laboratory propagation on Chlamydia trachomatis genome dynamics
V Borges, R Ferreira, A Nunes, M Sousa-Uva… - Infection, Genetics and …, 2013 - Elsevier
It is assumed that bacterial strains maintained in the laboratory for long time shape their
genome in a different fashion from the nature-circulating strains. Here, we analyzed the …
genome in a different fashion from the nature-circulating strains. Here, we analyzed the …
[HTML][HTML] Predicting phenotype and emerging strains among Chlamydia trachomatis infections
Chlamydia trachomatis is a global cause of blinding trachoma and sexually transmitted
infections (STIs). We used comparative genomics of the family Chlamydiaceae to select …
infections (STIs). We used comparative genomics of the family Chlamydiaceae to select …
Genomic and phenotypic characterization of in vitro-generated Chlamydia trachomatis recombinants
BM Jeffrey, RJ Suchland, SG Eriksen, KM Sandoz… - BMC microbiology, 2013 - Springer
Background Pre-genomic and post-genomic studies demonstrate that chlamydiae actively
recombine in vitro and in vivo, although the molecular and cellular biology of this process is …
recombine in vitro and in vivo, although the molecular and cellular biology of this process is …