Cell penetrating peptides: efficient vectors for delivery of nanoparticles, nanocarriers, therapeutic and diagnostic molecules

SM Farkhani, A Valizadeh, H Karami, S Mohammadi… - Peptides, 2014 - Elsevier
Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable …

Cell-penetrating peptides: breaking through to the other side

E Koren, VP Torchilin - Trends in molecular medicine, 2012 - cell.com
Cell-penetrating peptides (CPPs) have been previously shown to be powerful transport
vector tools for the intracellular delivery of a large variety of cargoes through the cell …

[HTML][HTML] Cell penetrating peptides: A concise review with emphasis on biomedical applications

H Derakhshankhah, S Jafari - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Introduction The biological membranes as natural permeable barriers are required for
survival and function of living cells. However, these natural barriers could be a major …

Intelligent substance delivery into cells using cell-penetrating peptides

T Tashima - Bioorganic & Medicinal Chemistry Letters, 2017 - Elsevier
Cell-penetrating peptides (CPPs) are oligopeptides that can permeate the cell membrane.
The use of a CPP-mediated transport system could be an excellent method for delivering …

Intracellular delivery of molecular cargo using cell-penetrating peptides and the combination strategies

H Li, TY Tsui, W Ma - International journal of molecular sciences, 2015 - mdpi.com
Cell-penetrating peptides (CPPs) can cross cellular membranes in a non-toxic fashion,
improving the intracellular delivery of various molecular cargos such as nanoparticles, small …

Potential efficacy of cell-penetrating peptides for nucleic acid and drug delivery in cancer

A Bolhassani - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2011 - Elsevier
Cell penetrating peptides (CPPs) are short amphipathic and cationic peptides that are
rapidly internalized across cell membranes. They can be used to deliver molecular cargo …

Cell-penetrating peptides: design, synthesis, and applications

DM Copolovici, K Langel, E Eriste, U Langel - ACS nano, 2014 - ACS Publications
The intrinsic property of cell-penetrating peptides (CPPs) to deliver therapeutic molecules
(nucleic acids, drugs, imaging agents) to cells and tissues in a nontoxic manner has …

Cell penetrating peptides in the delivery of biopharmaceuticals

WLL Munyendo, H Lv, H Benza-Ingoula, LD Baraza… - Biomolecules, 2012 - mdpi.com
The cell membrane is a highly selective barrier. This limits the cellular uptake of molecules
including DNA, oligonucleotides, peptides and proteins used as therapeutic agents …

Cell‐penetrating peptides: Nanocarrier for macromolecule delivery in living cells

A Chugh, F Eudes, YS Shim - IUBMB life, 2010 - Wiley Online Library
Novel classes and applications of cell‐penetrating peptides (CPPs) are being constantly
discovered since they were first identified 2 decades ago. These short cationic peptides …

Delivery of nucleic acids and nanomaterials by cell‐penetrating peptides: Opportunities and challenges

YW Huang, HJ Lee, LM Tolliver… - BioMed research …, 2015 - Wiley Online Library
Many viral and nonviral systems have been developed to aid delivery of biologically active
molecules into cells. Among these, cell‐penetrating peptides (CPPs) have received …