Introduction In modern drug design, in silico methods are largely used to understand drug-
receptor interactions and quantum chemical properties. In the present study, a …

Phyllanthus emblica is a traditional medicinal plant that is endowed with curative properties
including anti-bacterial, anti-fungal, anti-viral, and analgesic properties. Bacteria make use …

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Introduction: Quorum sensing inhibition (QSI) is one of the vital tools to overcome emerging …

Pseudomonas aeruginosa is an emerging opportunistic pathogen responsible for cystic
fibrosis and nosocomial infections. In addition, empirical treatments are become inefficient …

Quorum sensing (QS) is a bacterial communication strategy controlling cells density, biofilm
formation, virulence, sporulation, and survival. Since QS is considered a virulence factor in …

Drugs have been discovered in the past mainly either by identification of active components
from traditional remedies or by unpredicted discovery. A key motivation for the study of …

Natural products play vital roles against infectious diseases since ancient times and most
drugs in use today are derived from natural sources. Worldwide, multi-drug resistance …

Boronic acid compounds and the natural flavonoid compound quercetin were handled to
synthesize two novel ligands encoded as B1 (2, 2′-(1, 4-phenylenebis (benzo [1, 3, 2] …

Clinically significant pathogens such as Pseudomonas aeruginosa evade the effects of
antibiotics using quorum sensing (QS) systems, making antimicrobial resistance (AMR) a …

The emergence of multi-drug resistant bacteria in the past decades has become one of the
major public health issues of our time. One of the main mechanisms of resistance and …