Background Hypothalamic corticotropin‐releasing factor (CRF) receptor 1 (CRF1) plays a
role in acute stress‐related stimulation of colonic motor function. Less is known on CRF1 …

The colon has an autonomic activity owing to the concerted actions of the interstitial cells of
Cajal, the enteric nervous system (especially myentric plexus and submucosal plexus), and …

The objective of this study was to describe the correlation between changes in colonic
motility and defecatory disorders in four experimental canine models, with an emphasis on …

The enteric nervous system (ENS) plays an important role in regulating gastrointestinal (GI)
motility and can function independently of the central nervous system. Changes in ENS …

Postganglionic sympathetic neurons in the prevertebral ganglia (PVG) provide ongoing
inhibitory tone to the gastrointestinal tract and receive innervation from mechanosensory …

Objective To evaluate the roles of enteric nervous system neurotransmitters, nitric oxide
(NO), substance P (SP) and vasoactive intestinal polypeptide (VIP), and interstitial cells of …

Slow transit constipation (STC) is a common disease characterized by markedly delayed
colonic transit time as a result of colonic motility dysfunction. It is well established that STC is …

DiI (1, 1′ didodecyl‐3, 3, 3′, 3′‐tetramethylindocarbecyanine perchlorate) retrograde
labelling and intracellular electrophysiological techniques were used to investigate the …

In a fasting gastrointestinal tract, a characteristic cyclical rhythmic migrating motor complex
(MMC) occur that comprises of three phases: I, II, and III. Among these, phase III contractions …

Corticotropin releasing factor (CRF) is one of the most important factors in the mechanism of
stress-induced stimulation of colonic motility. However, it is controversial whether stress …