Obesity has related to the alteration of hormonal profiles, ie growth hormone (GH), insulin
and leptin. Because of the pleiotropic mechanisms of GH, it plays important roles both in the …

Background: Plasma leptin is regulated by several factors, including growth hormone (GH),
which influences the pathophysiology of obesity. Objective: To demonstrate the short-term …

Fasting substantially decreases plasma leptin concentration. However, in obesity, the fasting-
induced decrease in leptin concentration is blunted or absent. The objective of the current …

OBJECTIVES: To evaluate the plasma leptin concentration in lean and genetically obese
fa/fa rats and to assess the response to 2 h hyperinsulinaemia. BACKGROUND: The …

To investigate the response of plasma leptin and its diurnal variation to graded levels of
dietary fat intake, adult (486. 8±10.8 g), male rats (N= 52) were fed diets containing 12 …

The obese (ob) gene product leptin, secreted from adipose tissue, acts in the hypothalamus
to regulate body energy stores. In vitro experiments showed that insulin increases both …

This study was designed to test the hypothesis that short-term leptin infusion during the post-
obese refeeding phase of weight-reduced rats would reduce the rate of weight regain and …

Leptin, the product of the ob gene, has been reported to regulate feeding behavior and
energy metabolism. Plasma leptin concentration was strongly correlated with body fat …

The regulation of circulating leptin concentration is multifactorial and still understood.
Therefore, the present study was designed [1] to demonstrate the effect of gender on leptin …

The leptin [ob protein] is produced by adipocytes and is thought to act as an efferent signal
regulating body weight through suppressing appetite and stimulating energy expenditure in …