Background Understanding the role of circulating proteins in prostate cancer risk can reveal
key biological pathways and identify novel targets for cancer prevention. Methods We …

Background Understanding the role of circulating proteins in prostate cancer risk can reveal
key biological pathways and identify novel targets for cancer prevention. Methods We …

Prostate cancer (PCa) is a leading cause of cancer-related death in men. Understanding the
proteomic landscape associated with PCa risk can provide insights into its molecular …

Background The proteome is an important resource for exploring potential diagnostic and
therapeutic targets for cancer. This study aimed to investigate the causal associations …

Tumor-specific genomic aberrations are routinely determined by high throughput genomic
measurements. However, it is unclear how complex genome alterations affect molecular …

BACKGROUND More than 100 prostate cancer (PCa) risk‐associated single nucleotide
polymorphisms (SNPs) have been identified by genome wide association studies (GWAS) …

The genetic risk for prostate cancer has been governed by a few rare variants with high
penetrance and over 150 commonly occurring variants with lower impact on risk; however …

Prostate cancer (PC) is the most common malignancy observed in men. It is evident that
genetic factors play some important roles in PC etiology. Recently, genome‐wide …

Background Spatial and single-cell transcriptomics have revealed significant heterogeneity
in tumor and normal tissues. Each approach has its advantages: The Visium platform for …

Genome-wide association studies have identified multiple common alleles associated with
prostate cancer risk in populations of European ancestry. Testing these variants in other …