TIFA promotes colorectal cancer cell proliferation in an RSK‐and PRAS40‐dependent manner

W Shen, W Du, Y Li, Y Huang, X Jiang, C Yang… - Cancer …, 2022 - Wiley Online Library
Previous studies have reported that TIFA plays different roles in various tumor types.
However, the function of TIFA in colorectal cancer (CRC) remains unclear. Here, we showed …

TIFA, an inflammatory signaling adaptor, is tumor suppressive for liver cancer

W Shen, A Chang, J Wang, W Zhou, R Gao, J Li, Y Xu… - Oncogenesis, 2015 - nature.com
TIFA (TNF receptor associated factor (TRAF)-interacting protein with a Forkhead-associated
(FHA) domain), also called T2BP, was first identified using a yeast two-hybrid screening …

TIFA suppresses hepatocellular carcinoma progression via MALT1-dependent and-independent signaling pathways

W Shen, R Du, J Li, X Luo, S Zhao, A Chang… - … and Targeted Therapy, 2016 - nature.com
Abstract TIFA, also called T2BP, was first identified using yeast two-hybrid screening. Our
previous work showed that TIFA suppresses hepatocellular carcinoma (HCC) progression …

[HTML][HTML] TIFA promotes cell survival and migration in lung adenocarcinoma

W Men, W Li, J Zhao, Y Li - Cellular Physiology and Biochemistry, 2018 - karger.com
Background/Aims: TNF-α receptor-associated factor (TRAF)-interacting protein with a
forkhead-associated (FHA) domain (TIFA) may mediate the impact of TRAF on the …

TATA Box-Binding Protein–Associated Factor 12 Is Important for RAS-Induced Transformation Properties of Colorectal Cancer Cells

A Voulgari, S Voskou, L Tora, I Davidson… - Molecular Cancer …, 2008 - AACR
Activating mutations in the RAS proto-oncogene result in constant stimulation of its
downstream pathways, further leading to tumorigenesis. Transcription factor IID (TFIID) can …

[HTML][HTML] TFF3 promotes clonogenic survival of colorectal cancer cells through upregulation of EP4 via activation of STAT3

T Yang, X Fu, RF Tian, HY Cui, L Li… - Translational Cancer …, 2023 - ncbi.nlm.nih.gov
Background While growing evidence indicates the importance of TFF3 in cancer, the
molecular mechanism of its action in cancer remains largely unknown. Clonogenic survival …

TAF1 promotes NSCLC cell epithelial-mesenchymal transition by transcriptionally activating TGFβ1

J Zhang, R Li, B Zhang, X Cui - Biochemical and Biophysical Research …, 2022 - Elsevier
Despite tremendous advances in the diagnosis and treatment of NSCLC, the morbidity and
mortality of NSCLC still rank high worldwide. Epithelial-mesenchymal transition (EMT) is …

TCF21 functions as a tumor suppressor in colorectal cancer through inactivation of PI3K/AKT signaling

Y Dai, H Duan, C Duan, H Zhu, R Zhou… - OncoTargets and …, 2017 - Taylor & Francis
Colorectal cancer (CRC) has become a major public health problem, ranking as the third
most common type of cancer. Our previous study has revealed that TCF21 is frequently …

[HTML][HTML] The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis

C Chapard, D Hohl, M Huber - Oncotarget, 2015 - ncbi.nlm.nih.gov
The TRAF-interacting protein (TRAIP) is an E3 ubiquitin ligase required for cell proliferation.
TRAIP mRNA is downregulated in human keratinocytes after inhibition of the …

[HTML][HTML] TRAIP promotes malignant behaviors and correlates with poor prognosis in liver cancer

Z Guo, Y Zeng, Y Chen, M Liu, S Chen, M Yao… - Biomedicine & …, 2020 - Elsevier
TRAF-interacting protein (TRAIP) is a RING-type E3 ubiquitin ligase which has been
implicated in various cellular processes, including NF-κB activation, DNA damage response …