Investigational drugs for vasospasm after subarachnoid hemorrhage

RT Tallarico, MA Pizzi, WD Freeman - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Aneurysmal subarachnoid hemorrhage (aSAH) represents 3% of all strokes in
the US. When the patient survives it can lead to permanent incapacity especially if the …

Evidence-based cerebral vasospasm management

GW Weyer, CP Nolan, RL Macdonald - Neurosurgical focus, 2006 - thejns.org
✓ Cerebral vasospasm and delayed cerebral ischemia remain common complications of
aneurysmal subarachnoid hemorrhage (SAH), and yet therapies for cerebral vasospasm are …

Vasospasm after aneurysmal subarachnoid hemorrhage: review of randomized controlled trials and meta-analyses in the literature

GJ Velat, MM Kimball, JD Mocco, BL Hoh - World neurosurgery, 2011 - Elsevier
OBJECTIVE: Cerebral vasospasm is a major source of morbidity and mortality following
aneurysmal subarachnoid hemorrhage (SAH). A variety of therapies have been utilized to …

Evidence-based pharmacotherapy for cerebral vasospasm

EM Deshaies, AS Boulos, D Drazin… - Neurological …, 2009 - Taylor & Francis
Introduction: The vast amount of literature on the pharmaceutical treatment of cerebral
vasospasm after aneurysmal subarachnoid hemorrhage remains daunting. Optimal …

Medical management of cerebral vasospasm following aneurysmal subarachnoid hemorrhage: a review of current and emerging therapeutic interventions

P Adamczyk, S He, AP Amar… - Neurology research …, 2013 - Wiley Online Library
Cerebral vasospasm is a major source of morbidity and mortality in patients with aneurysmal
subarachnoid hemorrhage (aSAH). Evidence suggests a multifactorial etiology and this …

Clinical and experimental aspects of aneurysmal subarachnoid hemorrhage

BJ Daou, S Koduri, BG Thompson… - CNS neuroscience & …, 2019 - Wiley Online Library
Aneurysmal subarachnoid hemorrhage (aSAH) continues to be associated with significant
morbidity and mortality despite advances in care and aneurysm treatment strategies …

Vasospasm and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: recent advances and future directions in translational research

W Yu - Translational Stroke Research, 2023 - Springer
Aneurysmal subarachnoid hemorrhage (aSAH) affects approximately 6–9 individuals per
100,000 population [1]. Early repair of ruptured aneurysm by endovascular coiling or …

Beyond nimodipine: advanced neuroprotection strategies for aneurysmal subarachnoid hemorrhage vasospasm and delayed cerebral ischemia

S Luzzi, PK Bektaşoğlu, Y Doğruel, A Güngor - Neurosurgical review, 2024 - Springer
The clinical management of aneurysmal subarachnoid hemorrhage (SAH)-associated
vasospasm remains a challenge in neurosurgical practice, with its prevention and treatment …

Cerebral vasospasm in critically III patients with aneurysmal subarachnoid hemorrhage: does the evidence support the ever-growing list of potential pharmacotherapy …

TH Kiser - Hospital pharmacy, 2014 - journals.sagepub.com
The occurrence of cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH)
is a significant event resulting in decreased cerebral blood flow and oxygen delivery …

Current options for the management of aneurysmal subarachnoid hemorrhage-induced cerebral vasospasm: a comprehensive review of the literature

G Dabus, RG Nogueira - Interventional neurology, 2013 - karger.com
Objectives: Cerebral vasospasm is one of the leading causes of morbi-mortality following
aneurysmal subarachnoid hemorrhage. The aim of this article is to discuss the current status …