Modeling in colorectal cancer screening: assessing external and predictive validity of miscan-colon microsimulation model using norccap trial results

M Buskermolen, A Gini, SK Naber… - Medical Decision …, 2018 - journals.sagepub.com
Background. Microsimulation models are increasingly being used to inform colorectal
cancer (CRC) screening recommendations. MISCAN-Colon is an example of such a model …

Development and validation of three regional microsimulation models for predicting colorectal cancer screening benefits in Europe

A Gini, M Buskermolen, C Senore… - MDM Policy & …, 2021 - journals.sagepub.com
Background. Validated microsimulation models have been shown to be useful tools in
providing support for colorectal cancer (CRC) screening decisions. Aiming to assist …

Validation of colorectal cancer models on long-term outcomes from a randomized controlled trial

M DeYoreo, I Lansdorp-Vogelaar… - Medical Decision …, 2020 - journals.sagepub.com
Microsimulation models are often used to predict long-term outcomes and guide policy
decisions regarding cancer screening. The United Kingdom Flexible Sigmoidoscopy …

Validation of models used to inform colorectal cancer screening guidelines: accuracy and implications

CM Rutter, AB Knudsen, TL Marsh… - Medical Decision …, 2016 - journals.sagepub.com
Background. Microsimulation models synthesize evidence about disease processes and
interventions, providing a method for predicting long-term benefits and harms of prevention …

[HTML][HTML] Simulating results from trials of sigmoidoscopy screening using the OncoSim microsimulation model

A Coldman, J Pader, C Gauvreau, S Memon… - Journal of Cancer …, 2018 - Elsevier
Introduction Projection of the effect of cancer screening interventions are frequently
conducted using complex simulation models. It is important that such models demonstrate …

[HTML][HTML] Microsimulation model for prevention and intervention of coloretal cancer in China (MIMIC-CRC): development, calibration, validation, and application

B Lu, L Wang, M Lu, Y Zhang, J Cai, C Luo… - Frontiers in …, 2022 - frontiersin.org
Introduction A microsimulation model provides important references for decision-making
regarding colorectal cancer (CRC) prevention strategies, yet such a well-validated model is …

Impact of screening and follow‐up colonoscopy adenoma sensitivity on colorectal cancer screening outcomes in the CRC‐AIM microsimulation model

DA Fisher, L Saoud, K Hassmiller Lich… - Cancer …, 2021 - Wiley Online Library
Background Real‐world data for patients with positive colorectal cancer (CRC) screening
stool‐tests demonstrate that adenoma detection rates are lower when endoscopists are …

Effects of screening for colorectal cancer: development, documentation and validation of a multistate Markov model

T Heisser, M Hoffmeister… - International Journal of …, 2021 - Wiley Online Library
Simulation models are a powerful tool to overcome gaps of evidence needed to inform
medical decision‐making. Here, we present development and application of COSIMO, a …

An evidence-based microsimulation model for colorectal cancer: validation and application

CM Rutter, JE Savarino - Cancer epidemiology, biomarkers & prevention, 2010 - AACR
Abstract Background: The Colorectal Cancer Simulated Population model for Incidence and
Natural history (CRC-SPIN) is a new microsimulation model for the natural history of …

[HTML][HTML] CMOST: an open-source framework for the microsimulation of colorectal cancer screening strategies

MK Prakash, B Lang, H Heinrich, PV Valli… - BMC Medical Informatics …, 2017 - Springer
Background Colorectal cancer (CRC) is a leading cause of cancer-related mortality. CRC
incidence and mortality can be reduced by several screening strategies, including …